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Furoxan derivatives demonstrated in vivo efficacy by reducing Mycobacterium tuberculosis to undetectable levels in a mouse model of infection.
de Souza, P C; Fernandes, G F S; Marino, L B; Ribeiro, C M; Silva, P B da; Chorilli, M; Silva, C S P; Resende, F A; Solcia, M C; de Grandis, R A; Costa, C A S; Cho, S H; Wang, Y; Franzblau, S G; Dos Santos, J L; Pavan, F R.
Afiliación
  • de Souza PC; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil.
  • Fernandes GFS; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Department of Drugs and Medicines, Araraquara, São Paulo, 14800-903, Brazil.
  • Marino LB; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil.
  • Ribeiro CM; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil.
  • Silva PBD; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Department of Drugs and Medicines, Araraquara, São Paulo, 14800-903, Brazil.
  • Chorilli M; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Department of Drugs and Medicines, Araraquara, São Paulo, 14800-903, Brazil.
  • Silva CSP; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil.
  • Resende FA; Department of Biological Sciences and Health, UNIARA - University of Araraquara, Araraquara, São Paulo, 14801-340, Brazil.
  • Solcia MC; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil.
  • de Grandis RA; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil; Department of Biological Sciences and Health, UNIARA - University of Araraquara, Araraquara, São Paulo, 14801-340, Brazil.
  • Costa CAS; São Paulo State University (UNESP), School of Odontology, Department of Physiology and Pathology, Araraquara, São Paulo, 14801-903, Brazil.
  • Cho SH; Institute of Tuberculosis Research, UIC - University of Illinois at Chicago, Chicago, Illinois, 60612-7231, USA.
  • Wang Y; Institute of Tuberculosis Research, UIC - University of Illinois at Chicago, Chicago, Illinois, 60612-7231, USA.
  • Franzblau SG; Institute of Tuberculosis Research, UIC - University of Illinois at Chicago, Chicago, Illinois, 60612-7231, USA.
  • Dos Santos JL; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Department of Drugs and Medicines, Araraquara, São Paulo, 14800-903, Brazil.
  • Pavan FR; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Tuberculosis Research Laboratory, Araraquara, São Paulo, 14800-903, Brazil. Electronic address: fernando.pavan@unesp.br.
Biomed Pharmacother ; 130: 110592, 2020 Oct.
Article en En | MEDLINE | ID: mdl-32763822
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxadiazoles / Tuberculosis / Antituberculosos Límite: Animals Idioma: En Revista: Biomed Pharmacother Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Francia
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxadiazoles / Tuberculosis / Antituberculosos Límite: Animals Idioma: En Revista: Biomed Pharmacother Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Francia