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Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway.
Andersson, Claes R; Selvin, Tove; Blom, Kristin; Rubin, Jenny; Berglund, Malin; Jarvius, Malin; Lenhammar, Lena; Parrow, Vendela; Loskog, Angelica; Fryknäs, Mårten; Nygren, Peter; Larsson, Rolf.
Afiliación
  • Andersson CR; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden. claes.andersson@medsci.uu.se.
  • Selvin T; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden.
  • Blom K; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden.
  • Rubin J; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden.
  • Berglund M; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden.
  • Jarvius M; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden.
  • Lenhammar L; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden.
  • Parrow V; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden.
  • Loskog A; Department of Immunology, Genetics and Pathology, Section of Oncology, Uppsala University, 75185, Uppsala, Sweden.
  • Fryknäs M; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden.
  • Nygren P; Department of Immunology, Genetics and Pathology, Section of Oncology, Uppsala University, 75185, Uppsala, Sweden.
  • Larsson R; Division of Cancer Pharmacology and Computational Medicine, Department of Medical Sciences, Uppsala University, 75185, Uppsala, Sweden. rolf.larsson@medsci.uu.se.
Sci Rep ; 10(1): 13124, 2020 08 04.
Article en En | MEDLINE | ID: mdl-32753665
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Quinasas de Proteína Quinasa Activadas por Mitógenos / Sistema de Señalización de MAP Quinasas / Quinasas MAP Reguladas por Señal Extracelular / Mebendazol Límite: Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Quinasas de Proteína Quinasa Activadas por Mitógenos / Sistema de Señalización de MAP Quinasas / Quinasas MAP Reguladas por Señal Extracelular / Mebendazol Límite: Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido