Lung injury induced by short-term mechanical ventilation with hyperoxia and its mitigation by deferoxamine in rats.

Wang, Xiao-Xia; Sha, Xiao-Lan; Li, Yu-Lan; Li, Chun-Lan; Chen, Su-Heng; Wang, Jing-Jing; Xia, Zhengyuan

Wang, Xiao-Xia; Sha, Xiao-Lan; Li, Yu-Lan; Li, Chun-Lan; Chen, Su-Heng; Wang, Jing-Jing; Xia, Zhengyuan.

Afiliación

Wang XX; Department of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
Sha XL; Department of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
Li YL; Department of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China. east_tale@aliyun.com.
Li CL; Department of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
Chen SH; Department of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
Wang JJ; Department of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
Xia Z; Department of Anesthesiology, The University of Hong Kong, Hong Kong, 999077, People's Republic of China.

BMC Anesthesiol ; 20(1): 188, 2020 08 01.

Article en En | MEDLINE | ID: mdl-32738874

Asunto(s)

Deferoxamina/farmacología; Hiperoxia/complicaciones; Respiración Artificial/efectos adversos; Lesión Pulmonar Inducida por Ventilación Mecánica/prevención & control; Animales; Análisis de los Gases de la Sangre; Líquido del Lavado Bronquioalveolar; Masculino; Oxígeno/administración & dosificación; Ratas; Ratas Sprague-Dawley; Respiración Artificial/métodos; Sideróforos/farmacología; Factores de Tiempo

Palabras clave

Deferoxamine; Glutathion reductase; Hyperoxia acute lung injury; Lung surfactant protein; Mechanical ventilation; Xanthine oxidase

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Respiración Artificial / Hiperoxia / Deferoxamina / Lesión Pulmonar Inducida por Ventilación Mecánica Límite: Animals Idioma: En Revista: BMC Anesthesiol Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido

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