ISGylation of Hepatitis C Virus NS5A Protein Promotes Viral RNA Replication via Recruitment of Cyclophilin A.

Abe, Takayuki; Minami, Nanae; Bawono, Rheza Gandi; Matsui, Chieko; Deng, Lin; Fukuhara, Takasuke; Matsuura, Yoshiharu; Shoji, Ikuo

Abe, Takayuki; Minami, Nanae; Bawono, Rheza Gandi; Matsui, Chieko; Deng, Lin; Fukuhara, Takasuke; Matsuura, Yoshiharu; Shoji, Ikuo.

Afiliación

Abe T; Division of Infectious Disease Control, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan.
Minami N; Division of Infectious Disease Control, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan.
Bawono RG; Division of Infectious Disease Control, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan.
Matsui C; Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Deng L; Division of Infectious Disease Control, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan.
Fukuhara T; Division of Infectious Disease Control, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan.
Matsuura Y; Department of Molecular Virology, Research Institute for Microbial Diseases (RIMD), Osaka University, Osaka, Japan.
Shoji I; Department of Molecular Virology, Research Institute for Microbial Diseases (RIMD), Osaka University, Osaka, Japan.

J Virol ; 94(20)2020 09 29.

Article en En | MEDLINE | ID: mdl-32727878

Asunto(s)

Ciclofilina A/metabolismo; Citocinas/metabolismo; Hepacivirus/fisiología; Procesamiento Proteico-Postraduccional; ARN Viral/biosíntesis; Ubiquitinas/metabolismo; Proteínas no Estructurales Virales/metabolismo; Replicación Viral; Sustitución de Aminoácidos; Línea Celular; Ciclofilina A/genética; Citocinas/genética; Humanos; Mutación Missense; ARN Viral/genética; Ubiquitinas/genética; Proteínas no Estructurales Virales/genética

Palabras clave

ISGylation; cyclophilin A; hepatitis C virus; interferon; viral replication

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Replicación Viral / ARN Viral / Ubiquitinas / Procesamiento Proteico-Postraduccional / Citocinas / Proteínas no Estructurales Virales / Hepacivirus / Ciclofilina A Límite: Humans Idioma: En Revista: J Virol Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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