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Maturation of Intestinal Oxygenation: A Review of Mechanisms and Clinical Implications for Preterm Neonates.
Dotinga, Baukje M; Mintzer, Jonathan P; Moore, James E; Hulscher, Jan B F; Bos, Arend F; Kooi, Elisabeth M W.
Afiliación
  • Dotinga BM; Division of Neonatology, Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
  • Mintzer JP; Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Mountainside Medical Center, Montclair, NJ, United States.
  • Moore JE; Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Connecticut Children's Medical Center, University of Connecticut School of Medicine, Hartford, CT, United States.
  • Hulscher JBF; Division of Pediatric Surgery, Department of Surgery, University Medical Center Groningen, Groningen, Netherlands.
  • Bos AF; Division of Neonatology, Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
  • Kooi EMW; Division of Neonatology, Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Front Pediatr ; 8: 354, 2020.
Article en En | MEDLINE | ID: mdl-32719756
Nutrient requirements of preterm neonates may be substantial, to support growth and maturation processes in the presence of challenging post-natal circumstances. This may be accompanied by substantial intestinal oxygen requirements. Preterm neonates may not be able to meet these oxygen requirements, due to a developmental delay in intestinal oxygenation regulation mechanisms. This review summarizes the available literature on post-natal maturation of intestinal oxygenation mechanisms and translates these changes into clinical observations and potential implications for preterm neonates. The different mechanisms that may be involved in regulation of intestinal oxygenation, regardless of post-natal age, are first discussed. The contribution of these mechanisms to intestinal oxygenation regulation is then evaluated in newborn and mature intestine. Finally, the course of clinical observations is used to translate these findings to potential implications for preterm neonates.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Pediatr Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Pediatr Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Suiza