A small targeting domain in Ty1 integrase is sufficient to direct retrotransposon integration upstream of tRNA genes.

Asif-Laidin, Amna; Conesa, Christine; Bonnet, Amandine; Grison, Camille; Adhya, Indranil; Menouni, Rachid; Fayol, Hélène; Palmic, Noé; Acker, Joël; Lesage, Pascale

Asif-Laidin, Amna; Conesa, Christine; Bonnet, Amandine; Grison, Camille; Adhya, Indranil; Menouni, Rachid; Fayol, Hélène; Palmic, Noé; Acker, Joël; Lesage, Pascale.

Afiliación

Asif-Laidin A; INSERM U944, CNRS UMR 7212, Genomes& Cell Biology of Disease Unit, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Université de Paris, Paris, France.
Conesa C; CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, France.
Bonnet A; INSERM U944, CNRS UMR 7212, Genomes& Cell Biology of Disease Unit, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Université de Paris, Paris, France.
Grison C; INSERM U944, CNRS UMR 7212, Genomes& Cell Biology of Disease Unit, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Université de Paris, Paris, France.
Adhya I; CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, France.
Menouni R; INSERM U944, CNRS UMR 7212, Genomes& Cell Biology of Disease Unit, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Université de Paris, Paris, France.
Fayol H; INSERM U944, CNRS UMR 7212, Genomes& Cell Biology of Disease Unit, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Université de Paris, Paris, France.
Palmic N; INSERM U944, CNRS UMR 7212, Genomes& Cell Biology of Disease Unit, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Université de Paris, Paris, France.
Acker J; CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, France.
Lesage P; INSERM U944, CNRS UMR 7212, Genomes& Cell Biology of Disease Unit, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Université de Paris, Paris, France.

EMBO J ; 39(17): e104337, 2020 09 01.

Article en En | MEDLINE | ID: mdl-32677087

Asunto(s)

Integrasas/metabolismo; ARN Polimerasa III/metabolismo; ARN Polimerasa I/metabolismo; ARN de Transferencia/genética; Retroelementos; Proteínas de Saccharomyces cerevisiae/metabolismo; Saccharomyces cerevisiae/metabolismo; Integrasas/genética; ARN Polimerasa I/genética; ARN Polimerasa III/genética; Saccharomyces cerevisiae/genética; Proteínas de Saccharomyces cerevisiae/genética

Palabras clave

RNA Polymerases I and III; Ty1 retrotransposon; genome-wide de novo insertion sites; integrase genome-wide occupancy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Saccharomyces cerevisiae / ARN Polimerasa I / ARN Polimerasa III / ARN de Transferencia / Retroelementos / Integrasas / Proteínas de Saccharomyces cerevisiae Idioma: En Revista: EMBO J Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido

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