Identification of histone malonylation in the human fetal brain and implications for diabetes-induced neural tube defects.

Zhang, Qin; Cai, Tanxi; Xiao, Zonghui; Li, Dan; Wan, Chunlei; Cui, Xiaodai; Bai, Baoling

Zhang, Qin; Cai, Tanxi; Xiao, Zonghui; Li, Dan; Wan, Chunlei; Cui, Xiaodai; Bai, Baoling.

Afiliación

Zhang Q; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Cai T; Laboratory of Protein and Peptide Pharmaceuticals & Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xiao Z; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Li D; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Wan C; Weifang Medical University, Weifang, China.
Cui X; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Bai B; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.

Mol Genet Genomic Med ; 8(9): e1403, 2020 09.

Article en En | MEDLINE | ID: mdl-32666640

Asunto(s)

Histonas/metabolismo; Defectos del Tubo Neural/metabolismo; Embarazo en Diabéticas/metabolismo; Procesamiento Proteico-Postraduccional; Animales; Encéfalo/embriología; Encéfalo/metabolismo; Línea Celular; Epigénesis Genética; Femenino; Humanos; Lisina/metabolismo; Masculino; Malonatos/metabolismo; Ratones; Defectos del Tubo Neural/genética; Defectos del Tubo Neural/patología; Embarazo

Palabras clave

diabetes; histone lysine malonylation; mass spectrometry; neural tube defects

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Embarazo en Diabéticas / Histonas / Procesamiento Proteico-Postraduccional / Defectos del Tubo Neural Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Male / Pregnancy Idioma: En Revista: Mol Genet Genomic Med Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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