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Retrospective dose reconstruction of prostate stereotactic body radiotherapy using cone-beam CT and a log file during VMAT delivery with flattening-filter-free mode.
Imae, Toshikazu; Haga, Akihiro; Watanabe, Yuichi; Takenaka, Shigeharu; Shiraki, Takashi; Nawa, Kanabu; Ogita, Mami; Takahashi, Wataru; Yamashita, Hideomi; Nakagawa, Keiichi; Abe, Osamu.
Afiliación
  • Imae T; Department of Radiology, University of Tokyo Hospital, 3-7-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. imaet-rad@h.u-tokyo.ac.jp.
  • Haga A; Graduate School of Biomedical Science, Tokushima University, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
  • Watanabe Y; Faculty of Health Sciences, Komazawa University, 1-23-1Komazawa, Setagaya-ku, Tokyo, 154-8525, Japan.
  • Takenaka S; Department of Radiology, University of Tokyo Hospital, 3-7-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Shiraki T; Department of Radiology, University of Tokyo Hospital, 3-7-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Nawa K; Department of Radiology, University of Tokyo Hospital, 3-7-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Ogita M; Department of Radiology, University of Tokyo Hospital, 3-7-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Takahashi W; Department of Radiology, University of Tokyo Hospital, 3-7-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Yamashita H; Department of Radiology, University of Tokyo Hospital, 3-7-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Nakagawa K; Department of Radiology, University of Tokyo Hospital, 3-7-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Abe O; Department of Radiology, University of Tokyo Hospital, 3-7-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Radiol Phys Technol ; 13(3): 238-248, 2020 Sep.
Article en En | MEDLINE | ID: mdl-32656744
This study aimed to reconstruct the dose distribution of single fraction of stereotactic body radiotherapy for patients with prostate cancer using cone-beam computed tomography (CBCT) and a log file during volumetric-modulated arc therapy (VMAT) delivery with flattening-filter-free (FFF) mode. Twenty patients with clinically localized prostate cancer were treated with FFF-VMAT, and projection images for in-treatment CBCT (iCBCT) imaging were concomitantly acquired with a log file. A D95 dose of 36.25 Gy in five fractions was prescribed to each planning target volume (PTV) on each treatment planning CT (pCT). Deformed pCT (dCT) was obtained from the iCBCT using a hybrid deformable image registration algorithm. Dose distributions on the dCT were calculated using Pinnacle3 v9.10 by converting the log file data to Pinnacle3 data format using an in-house software. Dose warping was performed by referring to deformation vector fields calculated from pCT and dCT. Reconstructed dose distribution was compared with that of the original plan. Dose differences between the original and reconstructed dose distributions were within 3% at the isocenter and observed in PTV and organ-at-risk (OAR) regions. Differences in OAR regions were relatively larger than those in the PTV, presumably because OARs were more deformed than the PTV. Therefore, our method can be used successfully to reconstruct the dose distributions of one fraction using iCBCT and a log file during FFF-VMAT delivery.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Dosis de Radiación / Radiocirugia / Radioterapia de Intensidad Modulada / Tomografía Computarizada de Haz Cónico Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Humans / Male Idioma: En Revista: Radiol Phys Technol Asunto de la revista: BIOFISICA / RADIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Dosis de Radiación / Radiocirugia / Radioterapia de Intensidad Modulada / Tomografía Computarizada de Haz Cónico Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Humans / Male Idioma: En Revista: Radiol Phys Technol Asunto de la revista: BIOFISICA / RADIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón