Enhancement of the rewarding effects of 3,4-methylenedioxymethamphetamine in orexin knockout mice.

Mori, Tomohisa; Uzawa, Naoki; Masukawa, Daiki; Hirayama, Shigeto; Iwase, Yoshiyuki; Hokazono, Mayuna; Udagawa, Yuya; Suzuki, Tsutomu

Mori, Tomohisa; Uzawa, Naoki; Masukawa, Daiki; Hirayama, Shigeto; Iwase, Yoshiyuki; Hokazono, Mayuna; Udagawa, Yuya; Suzuki, Tsutomu.

Afiliación

Mori T; Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan; Department of Toxicology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan. Electronic address: t-mori@hoshi.ac.jp.
Uzawa N; Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan; Department of Toxicology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan.
Masukawa D; Department of Toxicology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan.
Hirayama S; Department of Toxicology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan.
Iwase Y; Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan; Department of Toxicology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan.
Hokazono M; Department of Toxicology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan.
Udagawa Y; Department of Toxicology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan.
Suzuki T; Department of Toxicology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan; Institute of Drug Addiction Research, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan. Electronic address: suzuki@hoshi.ac.jp.

Behav Brain Res ; 396: 112802, 2021 01 01.

Article en En | MEDLINE | ID: mdl-32653557

Asunto(s)

Estimulantes del Sistema Nervioso Central/farmacología; Condicionamiento Clásico/efectos de los fármacos; Metanfetamina/farmacología; Metilfenidato/farmacología; N-Metil-3,4-metilenodioxianfetamina/farmacología; Orexinas/deficiencia; Recompensa; Agonistas del Receptor de Serotonina 5-HT1/farmacología; Aprendizaje Espacial/efectos de los fármacos; Animales; Conducta Animal/efectos de los fármacos; Giro del Cíngulo/efectos de los fármacos; Giro del Cíngulo/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Núcleo Accumbens/efectos de los fármacos; Núcleo Accumbens/metabolismo

Palabras clave

5-HT; Discriminative stimulus effects; MDMA; Orexin; Rewarding effects

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recompensa / N-Metil-3,4-metilenodioxianfetamina / Condicionamiento Clásico / Agonistas del Receptor de Serotonina 5-HT1 / Aprendizaje Espacial / Orexinas / Estimulantes del Sistema Nervioso Central / Metanfetamina / Metilfenidato Límite: Animals Idioma: En Revista: Behav Brain Res Año: 2021 Tipo del documento: Article Pais de publicación: Países Bajos

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