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Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrier.
Hauptmann, Judith; Johann, Lisa; Marini, Federico; Kitic, Maja; Colombo, Elisa; Mufazalov, Ilgiz A; Krueger, Martin; Karram, Khalad; Moos, Sonja; Wanke, Florian; Kurschus, Florian C; Klein, Matthias; Cardoso, Silvia; Strauß, Judith; Bolisetty, Subhashini; Lühder, Fred; Schwaninger, Markus; Binder, Harald; Bechman, Ingo; Bopp, Tobias; Agarwal, Anupam; Soares, Miguel P; Regen, Tommy; Waisman, Ari.
Afiliación
  • Hauptmann J; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Johann L; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Marini F; Center of Thrombosis and Hemostasis Mainz (CTH), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Kitic M; Institute for Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Colombo E; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Mufazalov IA; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Krueger M; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Karram K; Anatomical Institute, University of Leipzig, Leipzig, Germany.
  • Moos S; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Wanke F; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Kurschus FC; Department of Dermatology, Heidelberg University Hospital, 69120, Heidelberg, Germany.
  • Klein M; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Cardoso S; Immunology, Infectious Diseases and Ophthalmology (I2O) Discovery and Translational Area Roche Innovation Center, Basel, Switzerland.
  • Strauß J; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Bolisetty S; Department of Dermatology, Heidelberg University Hospital, 69120, Heidelberg, Germany.
  • Lühder F; Institute for Immunology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Schwaninger M; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
  • Binder H; Instituto Gulbenkian de Ciência, Oeiras, Portugal.
  • Bechman I; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Göttingen, Germany.
  • Bopp T; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany.
  • Agarwal A; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Göttingen, Germany.
  • Soares MP; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany.
  • Regen T; Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
  • Waisman A; Anatomical Institute, University of Leipzig, Leipzig, Germany.
Acta Neuropathol ; 140(4): 549-567, 2020 10.
Article en En | MEDLINE | ID: mdl-32651669
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Barrera Hematoencefálica / Interleucina-1 / Células Endoteliales / Encefalomielitis Autoinmune Experimental / Hemo-Oxigenasa 1 / Inflamación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Acta Neuropathol Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Barrera Hematoencefálica / Interleucina-1 / Células Endoteliales / Encefalomielitis Autoinmune Experimental / Hemo-Oxigenasa 1 / Inflamación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Acta Neuropathol Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania