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[A new antiviral isoquinoline alkaloid from Thalictrum glandulosissimum].
Luo, Dian; Lyu, Na; Liao, Ling-Min; Gao, Qian; Li, Yin-Ke; Li, Jing; Liu, Xin; Li, Xue-Mei; Yang, Guang-Yu; Ye, Yan-Qing; Hu, Qiu-Fen; Dong, Miao.
Afiliación
  • Luo D; College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Lyu N; College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Liao LM; College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Gao Q; Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Li YK; College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Li J; Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Liu X; Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Li XM; Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Yang GY; College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Ye YQ; College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China.
  • Hu QF; College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.
  • Dong M; College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China.
Zhongguo Zhong Yao Za Zhi ; 45(11): 2568-2570, 2020 Jun.
Article en Zh | MEDLINE | ID: mdl-32627490
A new isoquinoline alkaloid(1) has been isolated from the whole plant of Thalictrum glandulosissimum by using various chromatographic techniques, including silica gel, sephadex, MCI-gel resin, and RP-HPLC, and its structure was determined as 1-(6-hydroxy-7-methylisoquinolin-1-yl) ethantone by physicochemical properties and spectroscopic data. This compound was evaluated for anti-tobacco mosaic virus(TMV) activity. The results showed that it had prominent anti-TMV activity with inhibition rates of 28.4%. This rate was closed to that of positive control.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Virus del Mosaico del Tabaco / Thalictrum / Alcaloides Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Asunto de la revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Virus del Mosaico del Tabaco / Thalictrum / Alcaloides Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Asunto de la revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: China