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Using a Fragment-Based Approach to Identify Alternative Chemical Scaffolds Targeting Dihydrofolate Reductase from Mycobacterium tuberculosis.
Ribeiro, João A; Hammer, Alexander; Libreros-Zúñiga, Gerardo A; Chavez-Pacheco, Sair M; Tyrakis, Petros; de Oliveira, Gabriel S; Kirkman, Timothy; El Bakali, Jamal; Rocco, Silvana A; Sforça, Mauricio L; Parise-Filho, Roberto; Coyne, Anthony G; Blundell, Tom L; Abell, Chris; Dias, Marcio V B.
Afiliación
  • Ribeiro JA; Department of Microbiology, Institute of Biomedical Science, University of São Paulo, Av. Prof. Lineu Prestes, 1474, São Paulo, SP 05508-000, Brazil.
  • Hammer A; Institute of Biology, University of Campinas, Cidade Universitária Zeferino Vaz, CEP, Campinas, SP 13083-862, Brazil.
  • Libreros-Zúñiga GA; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.
  • Chavez-Pacheco SM; Department of Microbiology, Institute of Biomedical Science, University of São Paulo, Av. Prof. Lineu Prestes, 1474, São Paulo, SP 05508-000, Brazil.
  • Tyrakis P; Department of Biology, IBILCE-State University of São Paulo, Rua Cristóvão Colombo, 2265, J. Nazareth, São José do Rio Preto, SP 15054-000, Brazil.
  • de Oliveira GS; Department of Microbiology, University of Valle, Calle 4B # 36-00, Cali 760043, Colombia.
  • Kirkman T; Department of Microbiology, Institute of Biomedical Science, University of São Paulo, Av. Prof. Lineu Prestes, 1474, São Paulo, SP 05508-000, Brazil.
  • El Bakali J; Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1GA, U.K.
  • Rocco SA; Department of Microbiology, Institute of Biomedical Science, University of São Paulo, Av. Prof. Lineu Prestes, 1474, São Paulo, SP 05508-000, Brazil.
  • Sforça ML; Department of Chemistry, University of Warwick, Gibbet Hill, Coventry CV4 7AL, U.K.
  • Parise-Filho R; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.
  • Coyne AG; National Laboratory of Biosciences, Rua Giuseppe Máximo Scolfaro, 10000, Campinas, SP 13083-100, Brazil.
  • Blundell TL; National Laboratory of Biosciences, Rua Giuseppe Máximo Scolfaro, 10000, Campinas, SP 13083-100, Brazil.
  • Abell C; Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, São Paulo, SP 05508-000, Brazil.
  • Dias MVB; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.
ACS Infect Dis ; 6(8): 2192-2201, 2020 08 14.
Article en En | MEDLINE | ID: mdl-32603583
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Antagonistas del Ácido Fólico / Mycobacterium tuberculosis Límite: Humans Idioma: En Revista: ACS Infect Dis Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Antagonistas del Ácido Fólico / Mycobacterium tuberculosis Límite: Humans Idioma: En Revista: ACS Infect Dis Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos