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Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism.
Gläser, Anne; Hammerl, Franziska; Gräler, Markus H; Coldewey, Sina M; Völkner, Christin; Frech, Moritz J; Yang, Fan; Luo, Jiankai; Tönnies, Eric; von Bohlen Und Halbach, Oliver; Brandt, Nicola; Heimes, Diana; Neßlauer, Anna-Maria; Korenke, Georg Christoph; Owczarek-Lipska, Marta; Neidhardt, John; Rolfs, Arndt; Wree, Andreas; Witt, Martin; Bräuer, Anja Ursula.
Afiliación
  • Gläser A; Research Group Anatomy, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, 26129 Oldenburg, Germany.
  • Hammerl F; Institute of Anatomy, Rostock University Medical Center, 18057 Rostock, Germany.
  • Gräler MH; Research Group Anatomy, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, 26129 Oldenburg, Germany.
  • Coldewey SM; Department of Anaesthesiology and Intensive Care Medicine, Center for Sepsis Control and Care (CSCC), Center for Molecular Biomedicine (CMB), Jena University Hospital, 07745 Jena, Germany.
  • Völkner C; Department of Anaesthesiology and Intensive Care Medicine, Septomics Research Center, Center for Sepsis Control and Care, Jena University Hospital, 07747 Jena, Germany.
  • Frech MJ; Translational Neurodegeneration Section "Albrecht Kossel", Department of Neurology, University Medical Center Rostock, University of Rostock, 18147 Rostock, Germany.
  • Yang F; Translational Neurodegeneration Section "Albrecht Kossel", Department of Neurology, University Medical Center Rostock, University of Rostock, 18147 Rostock, Germany.
  • Luo J; Center for Transdisciplinary Neurosciences Rostock (CTNR), Rostock University Medical Center, University of Rostock, 18147 Rostock, Germany.
  • Tönnies E; Translational Neurodegeneration Section "Albrecht Kossel", Department of Neurology, University Medical Center Rostock, University of Rostock, 18147 Rostock, Germany.
  • von Bohlen Und Halbach O; Translational Neurodegeneration Section "Albrecht Kossel", Department of Neurology, University Medical Center Rostock, University of Rostock, 18147 Rostock, Germany.
  • Brandt N; Center for Transdisciplinary Neurosciences Rostock (CTNR), Rostock University Medical Center, University of Rostock, 18147 Rostock, Germany.
  • Heimes D; Institute of Anatomy and Cell Biology, University Medicine Greifswald, 17487 Greifswald, Germany.
  • Neßlauer AM; Institute of Anatomy and Cell Biology, University Medicine Greifswald, 17487 Greifswald, Germany.
  • Korenke GC; Research Group Anatomy, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, 26129 Oldenburg, Germany.
  • Owczarek-Lipska M; Institute of Anatomy, Rostock University Medical Center, 18057 Rostock, Germany.
  • Neidhardt J; Institute of Anatomy, Rostock University Medical Center, 18057 Rostock, Germany.
  • Rolfs A; Department of Pediatrics, Klinikum Oldenburg, 26133 Oldenburg, Germany.
  • Wree A; Human Genetics, School of Medicine and Health Sciences, University of Oldenburg, 26129 Oldenburg, Germany.
  • Witt M; Junior Research Group, Genetics of childhood brain malformations, School of Medicine and Health Sciences, University of Oldenburg, 26129 Oldenburg, Germany.
  • Bräuer AU; Human Genetics, School of Medicine and Health Sciences, University of Oldenburg, 26129 Oldenburg, Germany.
Int J Mol Sci ; 21(12)2020 Jun 24.
Article en En | MEDLINE | ID: mdl-32599915
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esfingosina / Encéfalo / Lisofosfolípidos / 1-Desoxinojirimicina / Péptidos y Proteínas de Señalización Intracelular / Modelos Animales de Enfermedad / Enfermedad de Niemann-Pick Tipo C / Mutación Tipo de estudio: Diagnostic_studies Límite: Adult / Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esfingosina / Encéfalo / Lisofosfolípidos / 1-Desoxinojirimicina / Péptidos y Proteínas de Señalización Intracelular / Modelos Animales de Enfermedad / Enfermedad de Niemann-Pick Tipo C / Mutación Tipo de estudio: Diagnostic_studies Límite: Adult / Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza