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The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.
Hua, Peng; Hester, Joanna; Adigbli, George; Li, Rong; Psaila, Bethan; Roy, Anindita; Bataille, Carole J R; Wynne, Graham M; Jackson, Thomas; Milne, Thomas A; Russell, Angela J; Davies, James; Roberts, Irene; Issa, Fadi; Watt, Suzanne M.
Afiliación
  • Hua P; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine.
  • Hester J; Nuffield Division of Clinical Laboratory Medicine, Radcliffe Department of Medicine, University of Oxford.
  • Adigbli G; Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, and.
  • Li R; Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, and.
  • Psaila B; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine.
  • Roy A; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine.
  • Bataille CJR; Department of Paediatrics, University of Oxford, Children's Hospital, John Radcliffe Hospital, Oxford, United Kingdom.
  • Wynne GM; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, and.
  • Jackson T; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, and.
  • Milne TA; Department of Paediatrics, University of Oxford, Children's Hospital, John Radcliffe Hospital, Oxford, United Kingdom.
  • Russell AJ; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine.
  • Davies J; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, and.
  • Roberts I; Department of Pharmacology, University of Oxford, Oxford, United Kingdom; and.
  • Issa F; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine.
  • Watt SM; Nuffield Division of Clinical Laboratory Medicine, Radcliffe Department of Medicine, University of Oxford.
Blood ; 136(21): 2410-2415, 2020 11 19.
Article en En | MEDLINE | ID: mdl-32599615

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azepinas / Células Madre Hematopoyéticas / Megacariocitos / Proteínas / Trasplante de Células Madre de Sangre del Cordón Umbilical / Sangre Fetal / Acetamidas Límite: Animals / Humans Idioma: En Revista: Blood Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azepinas / Células Madre Hematopoyéticas / Megacariocitos / Proteínas / Trasplante de Células Madre de Sangre del Cordón Umbilical / Sangre Fetal / Acetamidas Límite: Animals / Humans Idioma: En Revista: Blood Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos