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Microglia promote glioblastoma via mTOR-mediated immunosuppression of the tumour microenvironment.
Dumas, Anaelle A; Pomella, Nicola; Rosser, Gabriel; Guglielmi, Loredana; Vinel, Claire; Millner, Thomas O; Rees, Jeremy; Aley, Natasha; Sheer, Denise; Wei, Jun; Marisetty, Anantha; Heimberger, Amy B; Bowman, Robert L; Brandner, Sebastian; Joyce, Johanna A; Marino, Silvia.
Afiliación
  • Dumas AA; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, UK.
  • Pomella N; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, UK.
  • Rosser G; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, UK.
  • Guglielmi L; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, UK.
  • Vinel C; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, UK.
  • Millner TO; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, UK.
  • Rees J; National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.
  • Aley N; Division of Neuropathology, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
  • Sheer D; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, UK.
  • Wei J; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Marisetty A; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Heimberger AB; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Bowman RL; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Brandner S; National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.
  • Joyce JA; Department of Oncology, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.
  • Marino S; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, UK.
EMBO J ; 39(15): e103790, 2020 08 03.
Article en En | MEDLINE | ID: mdl-32567735
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Microglía / Glioblastoma / Serina-Treonina Quinasas TOR / Microambiente Tumoral / Tolerancia Inmunológica / Proteínas de Neoplasias Límite: Animals / Humans Idioma: En Revista: EMBO J Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Microglía / Glioblastoma / Serina-Treonina Quinasas TOR / Microambiente Tumoral / Tolerancia Inmunológica / Proteínas de Neoplasias Límite: Animals / Humans Idioma: En Revista: EMBO J Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido