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Mini-Review on the Possible Interconnections between the Gut-Brain Axis and the Infertility-Related Neuropsychiatric Comorbidities.
Simionescu, Gabriela; Ilie, Ovidiu-Dumitru; Ciobica, Alin; Doroftei, Bogdan; Maftei, Radu; Grab, Delia; McKenna, Jack; Dhunna, Nitasha; Mavroudis, Ioannis; Anton, Emil.
Afiliación
  • Simionescu G; Department of Mother and Child Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", University Street, No 16, 700115 Iasi, Romania.
  • Ilie OD; Clinical Hospital of Obstetrics and Gynecology "Cuza Voda", Cuza Voda Street, No 34, 700038 Iasi, Romania.
  • Ciobica A; Origyn Fertility Center, Palace Street, No 3C, 700032 Iasi, Romania.
  • Doroftei B; Department of Research, Faculty of Biology, "Alexandru Ioan Cuza" University, Carol I Avenue, No 11, 700505 Iasi, Romania.
  • Maftei R; Department of Research, Faculty of Biology, "Alexandru Ioan Cuza" University, Carol I Avenue, No 11, 700505 Iasi, Romania.
  • Grab D; Department of Mother and Child Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", University Street, No 16, 700115 Iasi, Romania.
  • McKenna J; Clinical Hospital of Obstetrics and Gynecology "Cuza Voda", Cuza Voda Street, No 34, 700038 Iasi, Romania.
  • Dhunna N; Origyn Fertility Center, Palace Street, No 3C, 700032 Iasi, Romania.
  • Mavroudis I; Clinical Hospital of Obstetrics and Gynecology "Cuza Voda", Cuza Voda Street, No 34, 700038 Iasi, Romania.
  • Anton E; Origyn Fertility Center, Palace Street, No 3C, 700032 Iasi, Romania.
Brain Sci ; 10(6)2020 Jun 17.
Article en En | MEDLINE | ID: mdl-32560488
Both the gut-brain axis (GBA) and the hypothalamic-pituitary-adrenal (HPA) axis remain an intriguing yet obscure network with a strong influence over other systems of organs. Recent reports have sought to describe the multitude of harmful stressors that may impact the HPA axis along with the interconnections between these. This has improved our knowledge of how the underlying mechanisms working to establish homeostasis are affected. A disruption to the HPA axis can amplify the chances of gastrointestinal deficiencies, whilst also increasing the risk of a wide spectrum of neuropsychiatric disorders. Thus, the influence of microorganisms found throughout the digestive tract possess the ability to affect both physiology and behaviour by triggering responses, which may be unfavourable. This is sometimes the case in of infertility. Numerous supplements have been formulated with the intention of rebalancing the gut microflora. Accordingly, the gut flora may alter the pharmacokinetics of drugs used as part of fertility treatments, potentially exacerbating the predisposition for various neurological disorders, regardless of the age and gender.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Brain Sci Año: 2020 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Brain Sci Año: 2020 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Suiza