Your browser doesn't support javascript.
loading
Prophylactic photobiomodulation therapy using 660 nm diode laser for oral mucositis in paediatric patients under chemotherapy: 5-year experience from a Brazilian referral service.
Nunes, Laiz Fernandes Mendes; de Arruda, José Alcides Almeida; Souza, Alessandra Figueiredo; Silva, Raíssa Cristina Costa; Lanza, Célia Regina Moreira; Kakehasi, Fabiana Maria; Mesquita, Ricardo Alves; Abreu, Lucas Guimarães; Travassos, Denise Vieira; Silva, Tarcília Aparecida.
Afiliación
  • Nunes LFM; Dental Surgeon Residency, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • de Arruda JAA; Department of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, Room 3204, Belo Horizonte, MG, 31270-910, Brazil.
  • Souza AF; Department of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, Room 3204, Belo Horizonte, MG, 31270-910, Brazil.
  • Silva RCC; Dental Surgeon Residency, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Lanza CRM; Department of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, Room 3204, Belo Horizonte, MG, 31270-910, Brazil.
  • Kakehasi FM; Department of Paediatrics, School of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Mesquita RA; Department of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, Room 3204, Belo Horizonte, MG, 31270-910, Brazil.
  • Abreu LG; Department of Child's and Adolescent's Oral Health, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Travassos DV; Department of Community and Preventive Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Silva TA; Department of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, Room 3204, Belo Horizonte, MG, 31270-910, Brazil. silva.tarcilia@gmail.com.
Lasers Med Sci ; 35(8): 1857-1866, 2020 Oct.
Article en En | MEDLINE | ID: mdl-32535807
The use of photobiomodulation therapy (PBMT) in the prevention of oral mucositis (OM) in paediatric care has increased. In this article, we report data of paediatric oncology/haematopoietic stem cell transplantation (HSCT) patients treated with PBMT to prevent chemotherapy-induced OM. A retrospective study was conducted at a Brazilian referral service. Prophylactic PBMT was used in children and adolescents (≤ 17 years) following the protocol: InGaAIP, 660 nm, 100 mW, 2 J, 3.33 W/cm2, and 20 s per point. Demographic data and OM severity scores were assessed. A regression model tested the association between OM with prophylactic PBMT and antineoplastic therapy. A total of 148 individuals who had undergone 358 chemotherapy cycles were analysed. A higher occurrence of OM was observed in HSCT and osteosarcoma (OS) patients. Except for HSCT, OM was associated with methotrexate (MTX) use in all disease groups. PBMT significantly reduced OM severity in acute lymphoblastic leukaemia (ALL) and OS patients. OM grade was 3.16 and 5.45 times higher among individuals with ALL and OS, who had not undergone prophylactic PBMT compared with those who had undergone prophylactic PBMT (p < 0.001). PBMT prevented chemotherapy-induced OM. Individuals who used MTX and did not undergo prophylactic PBMT were at increased risk of OM.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estomatitis / Terapia por Luz de Baja Intensidad / Antineoplásicos Tipo de estudio: Guideline / Observational_studies / Prognostic_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Male País/Región como asunto: America do sul / Brasil Idioma: En Revista: Lasers Med Sci Asunto de la revista: BIOTECNOLOGIA / RADIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estomatitis / Terapia por Luz de Baja Intensidad / Antineoplásicos Tipo de estudio: Guideline / Observational_studies / Prognostic_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Male País/Región como asunto: America do sul / Brasil Idioma: En Revista: Lasers Med Sci Asunto de la revista: BIOTECNOLOGIA / RADIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido