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Development of a clinical score, PANDA, to predict delirium in stroke care unit.
Nakamizo, Tomoki; Kanda, Toshie; Kudo, Yosuke; Sugawara, Eriko; Hashimoto, Erina; Okazaki, Ayana; Usuda, Makoto; Nagai, Toru; Hara, Hiroshi; Johkura, Ken.
Afiliación
  • Nakamizo T; Department of Neurology, Yokohama Brain and Spine Center, Yokohama, Japan; Radiation Effects Research Foundation, Nagasaki, Japan.
  • Kanda T; Department of Nursing, Yokohama Brain and Spine Center, Yokohama, Japan.
  • Kudo Y; Department of Neurology, Yokohama Brain and Spine Center, Yokohama, Japan.
  • Sugawara E; Department of Neurology, Yokohama Brain and Spine Center, Yokohama, Japan.
  • Hashimoto E; Department of Nursing, Yokohama Brain and Spine Center, Yokohama, Japan.
  • Okazaki A; Department of Nursing, Yokohama Brain and Spine Center, Yokohama, Japan.
  • Usuda M; Department of Pharmacy, Yokohama Brain and Spine Center, Yokohama, Japan.
  • Nagai T; Department of Pharmacy, Yokohama Brain and Spine Center, Yokohama, Japan.
  • Hara H; Department of Pharmacy, Yokohama Brain and Spine Center, Yokohama, Japan.
  • Johkura K; Department of Neurology, Yokohama Brain and Spine Center, Yokohama, Japan. Electronic address: ke00-johkura@city.yokohama.jp.
J Neurol Sci ; 415: 116956, 2020 08 15.
Article en En | MEDLINE | ID: mdl-32505010
BACKGROUND AND PURPOSE: Delirium frequently complicates acute stroke and worsens outcomes. Because delirium is potentially preventable, predicting its occurrence is essential. Although several prediction scores have been proposed, nurses need to quickly predict delirium in stroke care units (SCUs). We aimed to develop a simple tool for this purpose by examining a comprehensive set of potential predictors. METHODS: This is a prospective cohort study on acute stroke patients admitted to an SCU. Patients without stupor, coma, or delirium upon admission were eligible. Participants were followed for 5 days from admission. Delirium was defined as Intensive Care Delirium Screening Checklist ≥4 points. We examined 27 potential predictors, of which 13 predictors were used to developed a least absolute shrinkage and selection operator-penalized logistic regression model. Five variables with the largest coefficients were assigned one point each in the prediction score. The internal validation was performed by bootstrapping. RESULTS: Delirium occurred in 42 of the 387 participants. The score consisted of prior delirium, alcohol, NIHSS ≥5, dementia, and auditory/visual impairment (PANDA). The apparent AUC was 0.84 (95% confidence interval [CI], 0.78-0.89), and the optimism-corrected AUC was 0.81 (95% CI, 0.73-0.88). With a cutoff of ≥2 points, sensitivity was 0.78 (95% CI, 0.65-0.90), and specificity was 0.74 (95% CI, 0.70-0.79). CONCLUSIONS: PANDA score is simple and predicts delirium in an SCU satisfactorily.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Accidente Cerebrovascular / Delirio Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Neurol Sci Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Accidente Cerebrovascular / Delirio Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Neurol Sci Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos