Preparation, statistical optimization, <i>in vitro</i> characterization, and <i>in vivo</i> pharmacological evaluation of solid lipid nanoparticles encapsulating propolis flavonoids: a novel treatment for skin edema.

Afra, Bahareh; Mohammadi, Mojdeh; Soleimani, Meysam; Mahjub, Reza

Preparation, statistical optimization, in vitro characterization, and in vivo pharmacological evaluation of solid lipid nanoparticles encapsulating propolis flavonoids: a novel treatment for skin edema.

Afra, Bahareh; Mohammadi, Mojdeh; Soleimani, Meysam; Mahjub, Reza.

Afiliación

Afra B; Department of Pharmaceutics, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
Mohammadi M; Department of Pharmacology and Toxicology, Hamadan University of Medical Sciences, Hamadan, Iran.
Soleimani M; Department of Pharmacology and Toxicology, Hamadan University of Medical Sciences, Hamadan, Iran.
Mahjub R; Department of Pharmaceutical Biotechnology, Hamadan University of Medical Sciences, Hamadan, Iran.

Drug Dev Ind Pharm ; 46(7): 1163-1176, 2020 Jul.

Article en En | MEDLINE | ID: mdl-32503368

Asunto(s)

Edema/tratamiento farmacológico; Flavonoides/farmacología; Lípidos/farmacología; Nanopartículas; Própolis; Animales; Portadores de Fármacos; Flavonoides/química; Lípidos/química; Ratas

Palabras clave

BoxBehnken response surface methodology; Propolis flavonoids; skin penetration; skin permeation; solid lipid nanoparticles (SLNs); topical anti-inflammatory properties

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Própolis / Flavonoides / Edema / Nanopartículas / Lípidos Límite: Animals Idioma: En Revista: Drug Dev Ind Pharm Año: 2020 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido

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