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Point-of-care tests for urinary tract infections: protocol for a systematic review and meta-analysis of diagnostic test accuracy.
Fraile Navarro, David; Sullivan, Frank; Azcoaga-Lorenzo, Amaya; Hernandez Santiago, Virginia.
Afiliación
  • Fraile Navarro D; Division of Population and Behavioural Sciences, School of Medicine, University of Saint Andrews, Saint Andrews, UK.
  • Sullivan F; Division of Population and Behavioural Sciences, School of Medicine, University of Saint Andrews, Saint Andrews, UK.
  • Azcoaga-Lorenzo A; Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Hernandez Santiago V; Division of Population and Behavioural Sciences, School of Medicine, University of Saint Andrews, Saint Andrews, UK.
BMJ Open ; 10(6): e033424, 2020 06 03.
Article en En | MEDLINE | ID: mdl-32499256
INTRODUCTION: Urinary tract infections (UTIs) are the second most common type of infection worldwide, accounting for a large number of primary care consultations and antibiotic prescribing. Current diagnosis is based on an empirical approach, relying on symptoms and occasional use of urine dipsticks. The diagnostic reference standard is still urine culture, although it is not routinely recommended for uncomplicated UTIs in the community, due to time to diagnosis (48 hours). Faster point-of-care tests have been developed, but their diagnostic accuracy has not been compared. Our objective is to systematically review and meta-analyse the diagnostic accuracy of currently available point-of-care tests for UTIs. METHODS AND ANALYSIS: Studies evaluating the diagnostic accuracy of point-of-care tests for UTIs will be included. PubMed, Web of Science, Embase and Cochrane Database of Systematic Reviews were searched from inception to 1 June 2019. Data extraction and risk-of-bias assessment will be assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. Meta-analysis will be performed depending on data availability and heterogeneity. ETHICS AND DISSEMINATION: This is a systematic review protocol and therefore formal ethical approval is not required, as no primary, identifiable, personal data will be collected. Patients or the public were not involved in the design of our research. However, the findings from this review will be shared with key stakeholders, including patient groups, clinicians and guideline developers, and will also be presented and national and international conferences. PROSPERO REGISTRATION NUMBER: CRD42018112019.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Urinarias / Pruebas en el Punto de Atención Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies / Systematic_reviews Aspecto: Ethics Límite: Humans Idioma: En Revista: BMJ Open Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Urinarias / Pruebas en el Punto de Atención Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies / Systematic_reviews Aspecto: Ethics Límite: Humans Idioma: En Revista: BMJ Open Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido