Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells.

Takahashi, Kazutoshi; Jeong, Daeun; Wang, Songnan; Narita, Megumi; Jin, Xuemei; Iwasaki, Mio; Perli, Samuel D; Conklin, Bruce R; Yamanaka, Shinya

Takahashi, Kazutoshi; Jeong, Daeun; Wang, Songnan; Narita, Megumi; Jin, Xuemei; Iwasaki, Mio; Perli, Samuel D; Conklin, Bruce R; Yamanaka, Shinya.

Afiliación

Takahashi K; Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. Electronic address: kazutoshi.takahashi@gladstone.ucsf.edu.
Jeong D; Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.
Wang S; Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.
Narita M; Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan.
Jin X; Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan.
Iwasaki M; Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan.
Perli SD; Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.
Conklin BR; Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA; Departments of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Ophthalmology, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Pharmacology,
Yamanaka S; Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA; Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA. Elec

Cell Rep ; 31(9): 107715, 2020 06 02.

Article en En | MEDLINE | ID: mdl-32492424

Asunto(s)

Diferenciación Celular; Retrovirus Endógenos/metabolismo; Neuronas/citología; Células Madre Pluripotentes/citología; ARN Viral/metabolismo; Animales; Arilamina N-Acetiltransferasa/deficiencia; Arilamina N-Acetiltransferasa/genética; Arilamina N-Acetiltransferasa/metabolismo; Línea Celular; Linaje de la Célula; Autorrenovación de las Células; Retrovirus Endógenos/genética; Edición Génica; Humanos; Isoenzimas/deficiencia; Isoenzimas/genética; Isoenzimas/metabolismo; Ratones; Neuronas/metabolismo; Iniciación de la Cadena Peptídica Traduccional; Células Madre Pluripotentes/metabolismo; Interferencia de ARN; ARN Nucleotidiltransferasas/genética; ARN Nucleotidiltransferasas/metabolismo; ARN Interferente Pequeño/metabolismo; ARN Viral/antagonistas & inhibidores; Factores de Transcripción/genética; Factores de Transcripción/metabolismo

Palabras clave

endogenous retrovirus; neural differentiation; pluripotency; translation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Viral / Diferenciación Celular / Retrovirus Endógenos / Células Madre Pluripotentes / Neuronas Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

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