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Neuroendocrine Tumour Of Unknown Primary Origin: Unusual Case Of Metastatic Hepatic Foci In A Female Patient.
Khan, Anosh Aslam; Bin Waqar, Syed Hamza; Mohiuddin, Osama; Ehtesham, Moiz; Jalees, Sumeen.
Afiliación
  • Khan AA; Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.
  • Bin Waqar SH; Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.
  • Mohiuddin O; Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.
  • Ehtesham M; Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.
  • Jalees S; Department of General Surgery, Dow University of Health Sciences, Karachi, Pakistan.
J Ayub Med Coll Abbottabad ; 32(1): 127-131, 2020.
Article en En | MEDLINE | ID: mdl-32468771
Under the banner of cancers of unknown primary origin (CUPs), neuroendocrine tumours account for less than five percent of the neoplasms. The clinical manifestations and management depend upon the tumour's grade and differentiation and its site of growth. At times, despite of aggressive search for primary origin, cancer remains hidden. Herein, we present a case of a middle-aged woman who presented to our tertiary set-up with complaints of abdominal pain and distension. After a series of radiologic and interventional investigations including positron emission tomography with liver biopsy and immunohistochemical analysis, a diagnosis of the welldifferentiated neuroendocrine tumour was made, located in the right lobe of the liver. However, the primary origin could not be identified. The patient was managed with trans-arterial chemoembolization (TACE) followed by hepatic resection and was followed biennially afterwards. In our case, hepatic metastasis was treated with chemoembolization and stagedresection and provided a good prognosis to the patient. Our case is unique as only a few case reports have been published with following presentation and documentation of efficacious treatment is needed to contribute to the literature. Proper trials with exteriorization of bowel and radiological imaging is necessary to stage the primary tumour, even if end result is in vain. This will help to further improve the prognosis.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Primarias Desconocidas / Tumores Neuroendocrinos / Neoplasias Hepáticas Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: J Ayub Med Coll Abbottabad Asunto de la revista: MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Pakistán Pais de publicación: Pakistán
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Primarias Desconocidas / Tumores Neuroendocrinos / Neoplasias Hepáticas Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: J Ayub Med Coll Abbottabad Asunto de la revista: MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Pakistán Pais de publicación: Pakistán