Copper mediates mitochondrial biogenesis in retinal pigment epithelial cells.

Aloysius Dhivya, M; Aberami, S; Nikhalashree, Sampath; Biswas, J; Liu, Wenjie; Irudayaraj, Joseph; Sulochana, K N; Coral, Karunakaran; Bharathi Devi, S R

Aloysius Dhivya, M; Aberami, S; Nikhalashree, Sampath; Biswas, J; Liu, Wenjie; Irudayaraj, Joseph; Sulochana, K N; Coral, Karunakaran; Bharathi Devi, S R.

Afiliación

Aloysius Dhivya M; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India; SASTRA deemed to be University, Trichy - Tanjore Road, Thirumalaisamudram, Thanjavur, Tamil Nadu 613401, India.
Aberami S; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India.
Nikhalashree S; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India; SASTRA deemed to be University, Trichy - Tanjore Road, Thirumalaisamudram, Thanjavur, Tamil Nadu 613401, India.
Biswas J; Department of Uveitis, Medical Research Foundation, India.
Liu W; Department of Bioengineering, Cancer Center at Illinois, Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Irudayaraj J; Department of Bioengineering, Cancer Center at Illinois, Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Sulochana KN; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India.
Coral K; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India. Electronic address: drkc@snmail.org.
Bharathi Devi SR; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India. Electronic address: drbarathi@snmail.org.

Biochim Biophys Acta Mol Basis Dis ; 1866(10): 165843, 2020 10 01.

Article en En | MEDLINE | ID: mdl-32454166

Asunto(s)

Cobre/metabolismo; Células Epiteliales/metabolismo; Degeneración Macular/metabolismo; Mitocondrias/metabolismo; Biogénesis de Organelos; Epitelio Pigmentado de la Retina/metabolismo; Pigmentos Retinianos/metabolismo; Anciano; Anciano de 80 o más Años; Línea Celular; Coroides/metabolismo; Cobre/farmacología; Transportador de Cobre 1/metabolismo; Proteínas de Unión al ADN/metabolismo; Complejo IV de Transporte de Electrones/metabolismo; Femenino; Regulación de la Expresión Génica/efectos de los fármacos; Humanos; Degeneración Macular/patología; Masculino; Mitocondrias/genética; Proteínas Mitocondriales/metabolismo; Chaperonas Moleculares/metabolismo; Factor 2 Relacionado con NF-E2/metabolismo; ARN Mensajero/metabolismo; Proteínas de Unión al ARN/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Epitelio Pigmentado de la Retina/patología; Pigmentos Retinianos/genética; Factores de Transcripción/metabolismo

Palabras clave

AMD; Copper; Mitochondrial biogenesis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pigmentos Retinianos / Biogénesis de Organelos / Cobre / Células Epiteliales / Epitelio Pigmentado de la Retina / Degeneración Macular / Mitocondrias Tipo de estudio: Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Año: 2020 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos

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