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Qualitative and quantitative analyses of phenol, phenylglucuronide, and phenylsulfate in urine and plasma by gas chromatography/mass spectrometry.
Pierce, W M; Nerland, D E.
Afiliación
  • Pierce WM; Department of Pharmacology and Toxicology, University of Louisville, School of Medicine, Kentucky 40292.
J Anal Toxicol ; 12(6): 344-7, 1988.
Article en En | MEDLINE | ID: mdl-3244274
Phenol and related compounds are toxic agents to which humans are exposed. Analysis of phenolic compounds may be used as an index of exposure. In this report a method for analysis of phenol, phenylglucuronide, phenylsulfate, and related mono- and dihydroxybenzenes as their propanoate esters by gas chromatography/mass spectrometry is presented. The use of this derivatization technique increases the sensitivity of the analysis by improving chromatographic performance and introducing a traceable "reporter" group into the analyte. This method has also been adapted, by using selected ion monitoring (SIM), to the quantitative analysis of phenol.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenoles / Ésteres del Ácido Sulfúrico / Ácidos Sulfúricos / Glucuronatos Tipo de estudio: Qualitative_research Límite: Humans Idioma: En Revista: J Anal Toxicol Año: 1988 Tipo del documento: Article Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenoles / Ésteres del Ácido Sulfúrico / Ácidos Sulfúricos / Glucuronatos Tipo de estudio: Qualitative_research Límite: Humans Idioma: En Revista: J Anal Toxicol Año: 1988 Tipo del documento: Article Pais de publicación: Reino Unido