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A novel in vivo model using immunotoxin in the absence of p-glycoprotein to achieve ultra selective depletion of target cells: Applications in trogocytosis and beyond.
Brown, Kathryn; Meader, Lucy; Nowocin, Anna; Edwards, Lindsey A; Cheung, Lawrence H; Smith, Richard A; Rosenblum, Michael G; Wong, Wilson.
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  • Brown K; MRC Centre for Transplantation, King's College London, School of Medicine at Guy's, King's and St. Thomas' Hospitals, London, UK.
  • Meader L; MRC Centre for Transplantation, King's College London, School of Medicine at Guy's, King's and St. Thomas' Hospitals, London, UK.
  • Nowocin A; MRC Centre for Transplantation, King's College London, School of Medicine at Guy's, King's and St. Thomas' Hospitals, London, UK; National Institute for Biological Standards and Control (NIBSC), Medicines and Healthcare Regulatory Agency, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG
  • Edwards LA; MRC Centre for Transplantation, King's College London, School of Medicine at Guy's, King's and St. Thomas' Hospitals, London, UK.
  • Cheung LH; National Institute for Biological Standards and Control (NIBSC), Medicines and Healthcare Regulatory Agency, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK.
  • Smith RA; MRC Centre for Transplantation, King's College London, School of Medicine at Guy's, King's and St. Thomas' Hospitals, London, UK.
  • Rosenblum MG; Immunopharmacology and Targeted Therapy Laboratory, Department of Experimental Therapeutics, Division of Cancer Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
  • Wong W; MRC Centre for Transplantation, King's College London, School of Medicine at Guy's, King's and St. Thomas' Hospitals, London, UK. Electronic address: wilson.wong@kcl.ac.uk.
J Immunol Methods ; 483: 112794, 2020 08.
Article en En | MEDLINE | ID: mdl-32428450
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunotoxinas / Depleción Linfocítica / Miembro 1 de la Subfamilia B de Casetes de Unión a ATP / Genes MDR / Citotoxicidad Inmunológica Límite: Animals Idioma: En Revista: J Immunol Methods Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunotoxinas / Depleción Linfocítica / Miembro 1 de la Subfamilia B de Casetes de Unión a ATP / Genes MDR / Citotoxicidad Inmunológica Límite: Animals Idioma: En Revista: J Immunol Methods Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Países Bajos