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Increased maternal new-onset psychiatric disorders after delivering a child with a major anomaly: a cohort study.
Rotberg, B; Horváth-Puhó, E; Vigod, S; Ray, J G; Sørensen, H T; Cohen, E.
Afiliación
  • Rotberg B; Department of Psychiatry, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
  • Horváth-Puhó E; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
  • Vigod S; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.
  • Ray JG; Department of Psychiatry, Women's College Hospital, University of Toronto, Toronto, ON, Canada.
  • Sørensen HT; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.
  • Cohen E; St. Michael's Hospital Department of Medicine, University of Toronto, Toronto, ON, Canada.
Acta Psychiatr Scand ; 142(4): 264-274, 2020 10.
Article en En | MEDLINE | ID: mdl-32406524
BACKGROUND: The birth of a child with a major congenital anomaly may create chronic caregiving stress for mothers, yet little is known about their psychiatric outcomes. AIMS: To evaluate the association of the birth of a child with a major congenital anomaly with subsequent maternal psychiatric risk. METHODS: This Danish nationwide cohort study included mothers who gave birth to an infant with a major congenital anomaly (n = 19 220) between 1997 and 2015. Comparators were randomly selected mothers, matched on maternal age, year of delivery and parity (n = 195 399). The primary outcome was any new-onset psychiatric diagnosis. Secondary outcomes included specific psychiatric diagnoses, psychiatric in-patient admissions and redeemed psychoactive medicines. Cox models were used to estimate hazard ratios (HRs), adjusted for socioeconomic and medical variables. RESULTS: Mothers of affected infants had an elevated risk for a new-onset psychiatric disorder vs. the comparison group (adjusted HR, 1.16, 95% CI 1.11-1.22). The adjusted HR was particularly elevated during the first postpartum year (1.65, 95% CI 1.42-1.90), but remained high for years, especially among mothers of children with multiorgan anomalies (1.37, 95% CI 1.18-1.57). The risk was also elevated for most specific psychiatric diagnoses, admissions and medicines. CONCLUSIONS: Mothers who give birth to a child with a major congenital anomaly are at increased risk of new-onset psychiatric disorders, especially shortly after birth and for mothers of children with more severe anomalies. Our study highlights the need to screen for mental illness in this high-risk population, as well as to integrate adult mental health services and paediatric care.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos Mentales / Madres Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Child / Female / Humans / Infant / Pregnancy Idioma: En Revista: Acta Psychiatr Scand Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos Mentales / Madres Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Child / Female / Humans / Infant / Pregnancy Idioma: En Revista: Acta Psychiatr Scand Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos