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Behcet's disease and pregnancy: a systematic review.
Merlino, Lucia; Del Prete, Federica; Lobozzo, Benedetta; Priori, Roberta; Piccioni, Maria G.
Afiliación
  • Merlino L; Department of Maternal and Child Health and Urological Sciences, Umberto I Polyclinic, Sapienza University, Rome, Italy.
  • Del Prete F; Department of Maternal and Child Health and Urological Sciences, Umberto I Polyclinic, Sapienza University, Rome, Italy - federica.delprete@uniroma1.it.
  • Lobozzo B; Department of Maternal and Child Health and Urological Sciences, Umberto I Polyclinic, Sapienza University, Rome, Italy.
  • Priori R; Unit of Rheumatology, Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy.
  • Piccioni MG; Department of Maternal and Child Health and Urological Sciences, Umberto I Polyclinic, Sapienza University, Rome, Italy.
Minerva Ginecol ; 72(5): 332-338, 2020 Oct.
Article en En | MEDLINE | ID: mdl-32403914
INTRODUCTION: Behcet's disease (BD) is a rare inflammatory, multisystemic, autoimmune disorder with unknown origin. BD is included in vasculitic disorders with a more frequent onset characterized by oral and genital ulcers associated with eye inflammation. However, BD has several clinical manifestations, and the most fearful complication is thrombotic involvement. BD occurs mainly in women of childbearing age, therefore it is important to identify the potential risks of pregnancy on the mother and fetus. EVIDENCE ACQUISITION: The aim of our review is to identify, through the study of existing literature, the possible consequences of pregnancy on the course of this disease, the potential risks for the mother and fetus in gestation period and in puerperium, in order to identify a correct pregnancy management in patient affected by BD. EVIDENCE SYNTHESIS: Currently, there are few studies that have analyzed the consequences of the disease on the course of pregnancy and pregnancy on the activity of the pathology. Some authors believe that pregnancy may worsen the symptoms of the disease, while others may even improve the course. Many authors believe that thromboembolic events are the main problems for which focus attention on these patients, both in pregnancy and in puerperium. Different opinions exist about pregnancy complications and neonatal outcomes, although events such as abortion, intrauterine growth restriction and C-section appear to have a higher incidence in BD patients. CONCLUSIONS: There are no contraindications for the onset of pregnancy in BD patients. In most cases pregnancy can improve the course of the disease. However, in view of the potential adverse events, a thorough follow-up of the pregnancy is necessary in order to minimize any risks to the mother and fetus.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Aborto Espontáneo / Síndrome de Behçet Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Minerva Ginecol Año: 2020 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Aborto Espontáneo / Síndrome de Behçet Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Minerva Ginecol Año: 2020 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia