Coordinated Action of miR-146a and Parkin Gene Regulate Rotenone-induced Neurodegeneration.

Jauhari, Abhishek; Singh, Tanisha; Mishra, Saumya; Shankar, Jai; Yadav, Sanjay

Jauhari, Abhishek; Singh, Tanisha; Mishra, Saumya; Shankar, Jai; Yadav, Sanjay.

Afiliación

Jauhari A; Systems Toxicology and Health Risk Assessment Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow 226001, Uttar Pradesh, India.
Singh T; Academy of Scientific and Innovative Research (AcSIR), CSIR-IITR Campus, New Delhi, India.
Mishra S; Department of Neurological Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Shankar J; Systems Toxicology and Health Risk Assessment Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow 226001, Uttar Pradesh, India.
Yadav S; Department of Neurological Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

Toxicol Sci ; 176(2): 433-445, 2020 08 01.

Article en En | MEDLINE | ID: mdl-32392329

Asunto(s)

MicroARNs; Mitocondrias/patología; Enfermedad de Parkinson Secundaria/genética; Rotenona/toxicidad; Ubiquitina-Proteína Ligasas/genética; Animales; Modelos Animales de Enfermedad; MicroARNs/genética; Mitofagia; FN-kappa B; Ratas

Palabras clave

Parkin; miR-146a; mitochondria; mitophagy; neurodegeneration; rotenone

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson Secundaria / Rotenona / MicroARNs / Ubiquitina-Proteína Ligasas / Mitocondrias Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Toxicol Sci Asunto de la revista: TOXICOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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