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[Treatment of chronic heart failure: is deprescribing possible?]
Tkacheva, O N; Ostroumova, O D; Kotovskaya, Yu V; Kochetkov, A I; Pereverzev, A P; Krasnov, G S.
Afiliación
  • Tkacheva ON; Russian Clinical and Research Center of Gerontology, N.I. Pirogov Russian National Research Medical University.
  • Ostroumova OD; Russian Clinical and Research Center of Gerontology, N.I. Pirogov Russian National Research Medical University.
  • Kotovskaya YV; Russian Clinical and Research Center of Gerontology, N.I. Pirogov Russian National Research Medical University.
  • Kochetkov AI; Russian Clinical and Research Center of Gerontology, N.I. Pirogov Russian National Research Medical University.
  • Pereverzev AP; Russian Clinical and Research Center of Gerontology, N.I. Pirogov Russian National Research Medical University.
  • Krasnov GS; Russian Clinical and Research Center of Gerontology, N.I. Pirogov Russian National Research Medical University.
Kardiologiia ; 60(3): 126-136, 2020 Jan 20.
Article en Ru | MEDLINE | ID: mdl-32375625
Deprescribing is a scheduled withdrawal, dose reduction, or replacement of a medicine with a safer one. Several groups of medicinal products (MPs) are used simultaneously in the treatment of chronic heart failure. This increases the risk of adverse drug reactions, particularly in elderly and senile patients. A systematic search for literature allowed evaluating possibilities of deprescribing for the following pharmaceutic groups: 1) MPs influencing the renin-angiotensin-aldosterone system; 2) beta-blockers; 3) digoxin; and 4) diuretics. Three systematic reviews and several studies were analyzed to determine the most feasible and potentially optimal regimens of deprescribing in CHF. It was established that in CHF, deprescribing has a very limited potential for use due to the documented, obvious effect of some MP groups on prediction and severity of clinical symptoms in CHF patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Deprescripciones / Insuficiencia Cardíaca Tipo de estudio: Prognostic_studies Límite: Aged / Humans Idioma: Ru Revista: Kardiologiia Año: 2020 Tipo del documento: Article Pais de publicación: Rusia
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Deprescripciones / Insuficiencia Cardíaca Tipo de estudio: Prognostic_studies Límite: Aged / Humans Idioma: Ru Revista: Kardiologiia Año: 2020 Tipo del documento: Article Pais de publicación: Rusia