Recent Advances in Synthetic Methods for Radioiodination.

Dubost, Emmanuelle; McErlain, Holly; Babin, Victor; Sutherland, Andrew; Cailly, Thomas

Dubost, Emmanuelle; McErlain, Holly; Babin, Victor; Sutherland, Andrew; Cailly, Thomas.

Afiliación

Dubost E; Normandie Univ, UNICAEN, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), 14000 Caen, France.
McErlain H; WestCHEM, School of Chemistry, The Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
Babin V; Normandie Univ, UNICAEN, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), 14000 Caen, France.
Sutherland A; WestCHEM, School of Chemistry, The Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
Cailly T; Normandie Univ, UNICAEN, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), 14000 Caen, France.

J Org Chem ; 85(13): 8300-8310, 2020 07 02.

Article en En | MEDLINE | ID: mdl-32369696

RESUMEN

Organic compounds bearing radioisotopes of iodine are widely used for biological research, diagnostic imaging, and radiotherapy. Early reported synthetic methods for the incorporation of radioiodine have generally involved high temperature reactions or strongly oxidizing conditions. To overcome these limitations and to cope with the demand for novel radioiodinated probes, there has been a surge in the development of new synthetic methodology for radioiodination. This synopsis describes the key transformations developed recently.

Asunto(s)

Radioisótopos de Yodo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Radioisótopos de Yodo Idioma: En Revista: J Org Chem Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos

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