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Debulking Surgery for Moderately Differentiated Neuroendocrine Gastric Carcinoma - A Case Report and Literature Review.
Bacalbasa, Nicolae; Halmaciu, Iuliana; Bolca, Ciprian; Neacsu, Adrian; Cretoiu, Dragos; Balalau, Cristian; Diaconu, Camelia; Iliescu, Laura; Filipescu, Alexandru; Pop, Cora; Balescu, Irina.
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  • Bacalbasa N; "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
  • Halmaciu I; Department of Obstetrics and Gynecology, "I. Cantacuzino" Clinical Hospital, Bucharest, Romania.
  • Bolca C; Department of Visceral Surgery, Center of Excellence in Translational Medicine "Fundeni" Clinical Institute, Bucharest, Romania.
  • Neacsu A; Department of Anatomy, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mures, Târgu Mures, Romania.
  • Cretoiu D; Department of Thoracic Surgery, "Marius Nasta" Institute of Pneumonology, Bucharest, Romania.
  • Balalau C; "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
  • Diaconu C; Department of Obstetrics and Gynecology, "St. John" Emergency Clinical Hospital, Bucharest, Romania.
  • Iliescu L; "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
  • Filipescu A; "Alessandrescu-Rusescu" National Institute of Mother and Child Health, Fetal Medicine Excellence Research Center, Bucharest, Romania.
  • Pop C; "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
  • Balescu I; Department of Surgery, "Pantelimon" Clinical Hospital, Bucharest, Romania.
In Vivo ; 34(3): 1527-1531, 2020.
Article en En | MEDLINE | ID: mdl-32354958
BACKGROUND/AIM: Gastroenteropancreatic neuro-endocrine carcinomas represent poorly differentiated neoplasms with a high capacity of spreading inducing the development of distant metastases. In such cases debulking surgery seems to offer a good chance for survival especially in well and moderately differentiated lesions. The aim of this study was to report the case of a 48-year-old patient submitted to surgery for moderately differentiated neuroendocrine gastric carcinoma with distant metastases. CASE REPORT: The patient was initially investigated for hematemesis and weight loss and was diagnosed with a lesser curvature gastric tumor in association with liver and peritoneal metastases. Due to the extent of the disease, the patient was initially submitted to neoadjuvant chemotherapy followed by surgery with radical intent. At the time of surgery subtotal gastrectomy en bloc with total omentectomy, peritonectomy, cholecystectomy and atypical liver resection were performed. Moreover, the two ovaries presented large tumoral masses so total hysterectomy with bilateral adnexectomy was performed. The histopathological studies confirmed the presence of a moderately differentiated neuroendocrine gastric carcinoma with negative resection margins. CONCLUSION: Multiple visceral resections might be needed in order to maximize the debulking effort in metastatic gastric neuroendocrine carcinomas.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Carcinoma Neuroendocrino / Procedimientos Quirúrgicos de Citorreducción Límite: Humans / Middle aged Idioma: En Revista: In Vivo Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Grecia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Carcinoma Neuroendocrino / Procedimientos Quirúrgicos de Citorreducción Límite: Humans / Middle aged Idioma: En Revista: In Vivo Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Grecia