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The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells.
Zhang, Jingjing; Gurusaran, Manickam; Fujiwara, Yasuhiro; Zhang, Kexin; Echbarthi, Meriem; Vorontsov, Egor; Guo, Rui; Pendlebury, Devon F; Alam, Intekhab; Livera, Gabriel; Emmanuelle, Martini; Wang, P Jeremy; Nandakumar, Jayakrishnan; Davies, Owen R; Shibuya, Hiroki.
Afiliación
  • Zhang J; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-40530, Gothenburg, Sweden.
  • Gurusaran M; Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, UK.
  • Fujiwara Y; Institute for Quantitative Biosciences, University of Tokyo, 1-1-1 Yayoi, Tokyo, 113-0032, Japan.
  • Zhang K; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-40530, Gothenburg, Sweden.
  • Echbarthi M; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-40530, Gothenburg, Sweden.
  • Vorontsov E; Proteomics Core Facility, Sahlgrenska Academy, University of Gothenburg, SE-40530, Gothenburg, Sweden.
  • Guo R; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, 19104, USA.
  • Pendlebury DF; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Alam I; Program in Chemical Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Livera G; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Emmanuelle M; Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Wang PJ; Laboratory of Development of the Gonads, UMRE008 Genetic Stability Stem Cells and Radiation, Université de Paris, Université Paris Saclay, CEA, F-92265, Fontenay aux Roses, France.
  • Nandakumar J; Laboratory of Development of the Gonads, UMRE008 Genetic Stability Stem Cells and Radiation, Université de Paris, Université Paris Saclay, CEA, F-92265, Fontenay aux Roses, France.
  • Davies OR; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, 19104, USA.
  • Shibuya H; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Nat Commun ; 11(1): 2055, 2020 04 28.
Article en En | MEDLINE | ID: mdl-32345962
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína BRCA2 / Complejos Multiproteicos / Recombinasa Rad51 / Recombinación Homóloga / Meiosis / Mitosis / Neoplasias Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína BRCA2 / Complejos Multiproteicos / Recombinasa Rad51 / Recombinación Homóloga / Meiosis / Mitosis / Neoplasias Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido