Studies of the labile lead pool using a rhodamine-based fluorescent probe.
Metallomics
; 12(5): 644-648, 2020 05 27.
Article
en En
| MEDLINE
| ID: mdl-32342963
Lead is a heavy metal which has long been known to have toxic effects on the body. However, much remains to be learnt about the labile lead pool and cellular uptake of lead. We report here RPb1 that undergoes a 100-fold increase in fluorescence emission in the presence of Pb2+, and which can be applied to study the labile lead pool within cells. We demonstrate the capacity of RPb1 for investigating labile lead pool in DLD-1 cells and changes in labile lead during differentiation of K562 cells.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Rodaminas
/
Neoplasias del Colon
/
Colorantes Fluorescentes
/
Plomo
Límite:
Humans
Idioma:
En
Revista:
Metallomics
Asunto de la revista:
BIOQUIMICA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Australia
Pais de publicación:
Reino Unido