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HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells.
Nguyen, Diu T T; Lu, Yuheng; Chu, Karen L; Yang, Xuejing; Park, Sun-Mi; Choo, Zi-Ning; Chin, Christopher R; Prieto, Camila; Schurer, Alexandra; Barin, Ersilia; Savino, Angela M; Gourkanti, Saroj; Patel, Payal; Vu, Ly P; Leslie, Christina S; Kharas, Michael G.
Afiliación
  • Nguyen DTT; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Lu Y; Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chu KL; Blavatnik Institute of System Biology, Harvard Medical School, Boston, MA, 02115, USA.
  • Yang X; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Park SM; Weill Cornell School of Medical Sciences, New York, NY, 10065, USA.
  • Choo ZN; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Chin CR; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Prieto C; Weill Cornell School of Medical Sciences, New York, NY, 10065, USA.
  • Schurer A; Weill Cornell School of Medical Sciences, New York, NY, 10065, USA.
  • Barin E; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Savino AM; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Gourkanti S; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Patel P; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Vu LP; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Leslie CS; Weill Cornell School of Medical Sciences, New York, NY, 10065, USA.
  • Kharas MG; Terry Fox Laboratory, British Columbia Cancer Research Centre, Vancouver, BC, V5Z 1L3, Canada.
Nat Commun ; 11(1): 2026, 2020 04 24.
Article en En | MEDLINE | ID: mdl-32332729

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Células Madre Hematopoyéticas / Leucemia / Diferenciación Celular / Proteínas de Unión al ARN Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Células Madre Hematopoyéticas / Leucemia / Diferenciación Celular / Proteínas de Unión al ARN Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido