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Results of endocavitary irradiation of early rectal tumors.
Roth, S L; Horiot, J C; Calais, G; Nabid, A; Bone, M C.
Afiliación
  • Roth SL; Service de Radiotherapie, Centre Lutte Contre le Cancer, Dijon, France.
Acta Oncol ; 27(6b): 825-7, 1988.
Article en En | MEDLINE | ID: mdl-3233169
At the C. G. F. Leclerc, Dijon, 91 early rectal tumors were treated with intracavitary contact radiotherapy alone or in combination with interstitial brachytherapy. The median age of the patients was 70 years. Most of them were referred because of poor surgical risk. Preservation of the sphincter was obtained in 85% (77/91). The actuarial local relapse-free survival rate at 5 years was 74% (67/91). No significant difference was seen between the 72 adenocarcinomas and 19 villous adenomas (p = 0.12). For the middle rectum the rate was 94% compared to 54% for the upper and 77% for the lower rectum. Anterior primaries fared better than posterior and lateral tumors (100%, 63%, and 67% respectively). After salvage therapy the local control rate raised to 91% (83/91). The clinical and endoscopic staging system of Dijon was of prognostic significance: T1A adenocarcinomas (purely exophytic tumors of less than 3 cm) had a better 5-year local relapse-free survival rate (97%) than T2A, T1B or T2B (p less than 0.01).
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Recto / Braquiterapia Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Oncol Asunto de la revista: NEOPLASIAS Año: 1988 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Recto / Braquiterapia Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Oncol Asunto de la revista: NEOPLASIAS Año: 1988 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido