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Discovery and Development of S6821 and S7958 as Potent TAS2R8 Antagonists.
Fotsing, Joseph R; Darmohusodo, Vincent; Patron, Andrew P; Ching, Brett W; Brady, Thomas; Arellano, Melissa; Chen, Qing; Davis, Timothy J; Liu, Hanghui; Servant, Guy; Zhang, Lan; Williams, Mark; Saganich, Michael; Ditschun, Tanya; Tachdjian, Catherine; Karanewsky, Donald S.
Afiliación
  • Fotsing JR; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Darmohusodo V; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Patron AP; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Ching BW; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Brady T; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Arellano M; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Chen Q; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Davis TJ; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Liu H; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Servant G; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Zhang L; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Williams M; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Saganich M; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Ditschun T; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Tachdjian C; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
  • Karanewsky DS; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
J Med Chem ; 63(9): 4957-4977, 2020 05 14.
Article en En | MEDLINE | ID: mdl-32330040
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Gusto / Receptores de Superficie Celular / Receptores Acoplados a Proteínas G / Hidantoínas Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Gusto / Receptores de Superficie Celular / Receptores Acoplados a Proteínas G / Hidantoínas Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos