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Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1,2,4-triazole derivatives their molecular docking and kinetic studies.
Yeye, Emmanuel Oloruntoba; Mohammed Khan, Khalid; Chigurupati, Sridevi; Wadood, Abdul; Ur Rehman, Ashfaq; Perveen, Shahnaz; Kannan Maharajan, Mari; Shamim, Shahbaz; Hameed, Shehryar; Aboaba, Sherifat A; Taha, Muhammad.
Afiliación
  • Yeye EO; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan; Organic Unit, Chemistry Department, University of Ibadan, Nigeria.
  • Kanwal; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
  • Mohammed Khan K; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam
  • Chigurupati S; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Qassim University, Buraidah 52571, Saudi Arabia.
  • Wadood A; Department of Biochemistry, Computational Medicinal Chemistry Laboratory, UCSS, Abdul Wali Khan University, Mardan, Pakistan.
  • Ur Rehman A; Department of Biochemistry, Computational Medicinal Chemistry Laboratory, UCSS, Abdul Wali Khan University, Mardan, Pakistan.
  • Perveen S; PCSIR Laboratories Complex, Karachi, Shahra-e-Dr. Salimuzzaman Siddiqui, Karachi 75280, Pakistan.
  • Kannan Maharajan M; School of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia.
  • Shamim S; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
  • Hameed S; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
  • Aboaba SA; Organic Unit, Chemistry Department, University of Ibadan, Nigeria.
  • Taha M; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
Bioorg Med Chem ; 28(11): 115467, 2020 06 01.
Article en En | MEDLINE | ID: mdl-32327353
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triazoles / Alfa-Amilasas / Alfa-Glucosidasas / Simulación del Acoplamiento Molecular / Inhibidores de Glicósido Hidrolasas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triazoles / Alfa-Amilasas / Alfa-Glucosidasas / Simulación del Acoplamiento Molecular / Inhibidores de Glicósido Hidrolasas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Reino Unido