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Evaluation of Cytotoxicity and Mutagenicity of Wastewater from Istanbul: Data from Hospitals and Advanced Wastewater Treatment Plant.
Cevik, Mehtap; Dartan, Guler; Ulker, Melike; Bezci, Kivanç; Deliorman, Gokce; Cagatay, Penbe; Lacin, Tunc; Cinel, Ismail Hakki; Aksu, Burak; Keskin, Yasar; Can, Zehra Semra; Yurdun, Turkan; Susleyici, Belgin.
Afiliación
  • Cevik M; Division of Biology, Department of Molecular Biology, Faculty of Arts and Sciences, Marmara University, Istanbul, Turkey.
  • Dartan G; Division of Chemistry, Department of Analytical Chemistry, Faculty of Arts and Sciences, Marmara University, Istanbul, Turkey.
  • Ulker M; Division of Biology, Department of Molecular Biology, Faculty of Arts and Sciences, Marmara University, Istanbul, Turkey.
  • Bezci K; Division of Biology, Department of Molecular Biology, Faculty of Arts and Sciences, Marmara University, Istanbul, Turkey.
  • Deliorman G; Division of Statistics, Faculty of Arts and Sciences, Marmara University, Istanbul, Turkey.
  • Cagatay P; Department of Medical Services and Technics, Vocational School of Health Service, Istanbul University - Cerrahpasa, Istanbul, Turkey.
  • Lacin T; Department of Thoracic Surgery, Faculty of Medicine, Marmara University, Istanbul, Turkey.
  • Cinel IH; Department of Anesthesiology and Intensive Care, Faculty of Medicine, Marmara University, Istanbul, Turkey.
  • Aksu B; Department of Medical Microbiology, Faculty of Medicine, Marmara University, Istanbul, Turkey.
  • Keskin Y; Department of Public Health, Faculty of Medicine, Marmara University, Istanbul, Turkey.
  • Can ZS; Department of Environmental Engineering, Marmara University, Istanbul, Turkey.
  • Yurdun T; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Marmara University, Istanbul, Turkey.
  • Susleyici B; Division of Biology, Department of Molecular Biology, Faculty of Arts and Sciences, Marmara University, Istanbul, Turkey. belginsusleyici@gmail.com.
Bull Environ Contam Toxicol ; 104(6): 852-857, 2020 Jun.
Article en En | MEDLINE | ID: mdl-32322934
Wastewater (WW) carry considerable amount of chemicals that could have mutagenic or cytotoxic effect from hospital discharges to aquatic environment. Our objective was to determinate the possible mutagenic and toxic effects of hospital originated WWs and effectiveness of the wastewater treatment plants (WTP) functions. In the study the mutagenic and cytotoxic potential of three hospitals and influent/effluent of a treatment plant WW collected in Istanbul and was examined using AMES, XTT, and lactate dehydrogenase (LDH) assays. Mutagenic effects were detected at both hospital discharges and advanced biological wastewater plant. We observed no cytotoxic effect in fibroblasts for LDH and XTT assays whereas high cytotoxicity for all samples was found in hepatocytes by XTT assay. According to the results even if advanced technology is used for treatment of WW, mutagenic and cytotoxic effects still remain, and the present technologies need to be further improved.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Eliminación de Residuos Líquidos / Purificación del Agua / Aguas Residuales / Mutágenos Límite: Animals Idioma: En Revista: Bull Environ Contam Toxicol Año: 2020 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Eliminación de Residuos Líquidos / Purificación del Agua / Aguas Residuales / Mutágenos Límite: Animals Idioma: En Revista: Bull Environ Contam Toxicol Año: 2020 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos