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Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study.
Jordão, Paula Moskovics; Russomano, Fábio Bastos; Gerbauld, Gabriella Tostes; Andrade, Cecília Vianna de; Osorio, Clarice Fraga Esteves Maciel.
Afiliación
  • Jordão PM; MD. Postgraduate Student, Physician and Gynecologist, Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro (RJ), Brazil.
  • Russomano FB; MD, PhD. Physician, Gynecologist and Professor of Postgraduate Studies, Women's Health Sector, Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro (RJ), Brazil.
  • Gerbauld GT; MD, Postgraduate Student, Physician and Gynecologist, Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro (RJ), Brazil.
  • Andrade CV; MD, PhD. Physician, Pathologist and Professor of Postgraduate Studies, Diagnostic and Therapeutic Coordination for Pathological Anatomy and Cytopathology, Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro (RJ), Braz
  • Osorio CFEM; MD, MSc. Physician and Cytopathologist, Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro (RJ), Brazil.
Sao Paulo Med J ; 138(1): 47-53, 2020.
Article en En | MEDLINE | ID: mdl-32321105
BACKGROUND: Cervical cancer screening in Brazil is done using Pap smears. Women who are most likely to have a preinvasive lesion or cervical cancer are immediately referred for colposcopy. OBJECTIVE: The aim of this study was to evaluate the diagnostic performance of endocervical cytological tests in diagnosing preinvasive cervical lesions in women with initial high-grade squamous intraepithelial lesions (HSIL), or atypical squamous cells in which high-grade lesions could not be ruled out (ASC-H), or atypical glandular cells (AGC), and whose colposcopy did not show any abnormalities, with no fully visible transformation zone (types 2 and 3). DESIGN AND SETTING: Retrospective observational study conducted in Rio de Janeiro, Brazil. METHODS: Data from women who came to the cervical pathology outpatient clinic between January 2012 and April 2017 were analyzed. The results from endocervical cytological tests were compared with the final diagnosis, which was obtained through examination of a surgical specimen or, among women who did not undergo an excisional procedure, after cytological and colposcopic follow-up for two years. RESULTS: We included 78 women. The sensitivity of endocervical cytological tests was 72.7%; specificity 98.5%; positive and negative predictive values 88.9% and 95.6%, respectively; and positive and negative likelihood ratios 48.7 and 0.28. CONCLUSION: Endocervical cytological tests are simple, inexpensive and noninvasive, and form a reliable method for determining management among patients with HSIL, ASC-H and AGC cytological findings and negative colposcopic findings without visualization of the squamocolumnar junction.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Displasia del Cuello del Útero / Neoplasias del Cuello Uterino Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Screening_studies Límite: Female / Humans / Pregnancy País/Región como asunto: America do sul / Brasil Idioma: En Revista: Sao Paulo Med J Asunto de la revista: MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Displasia del Cuello del Útero / Neoplasias del Cuello Uterino Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Screening_studies Límite: Female / Humans / Pregnancy País/Región como asunto: America do sul / Brasil Idioma: En Revista: Sao Paulo Med J Asunto de la revista: MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil