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Did the Clinical Spectrum of Thromboangiitis Obliterans Change in the Past 40 Years?
Soudet, Simon; Le Joncour, Alexandre; Quemeneur, Thomas; Maillard, Helene; Koskas, Fabien; Hachulla, Eric; Cacoub, Patrice; Yelnik, Cecile M; Saadoun, David; Lambert, Marc.
Afiliación
  • Soudet S; Department of Internal Medicine, Hôpital HURIEZ, CHRU Lille, France.
  • Le Joncour A; Department of Internal Medicine and Clinical Immunology, Centre de Référence des Maladies Auto-Immunes et Systémiques Rares, des Maladies Auto-Inflammatoires et de l'Amylose, Paris, France.
  • Quemeneur T; AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
  • Maillard H; Sorbonne Université, UPMC Univ Paris 06, UMR 7211, France.
  • Koskas F; Department of Nephrology and Internal Medicine, Valenciennes Hospital, France.
  • Hachulla E; Department of Internal Medicine, Hôpital HURIEZ, CHRU Lille, France.
  • Cacoub P; Department of Vascular Surgery, Assistance Publique des Hôpitaux de Paris, Hôpital Pitié Salpêtrière, Paris, France.
  • Yelnik CM; Department of Internal Medicine, Hôpital HURIEZ, CHRU Lille, France.
  • Saadoun D; Department of Internal Medicine and Clinical Immunology, Centre de Référence des Maladies Auto-Immunes et Systémiques Rares, des Maladies Auto-Inflammatoires et de l'Amylose, Paris, France.
  • Lambert M; AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Angiology ; 71(7): 621-625, 2020 08.
Article en En | MEDLINE | ID: mdl-32319306
Thromboangiitis obliterans (TAO) is an inflammatory disease that usually affects small and medium-sized arteries in the upper and lower limbs of young smokers. Previous studies showed that the spectrum TAO has changed in the 80s: the male-to-female ratio decreased, older patients were diagnosed, and upper limb involvement was more common. The aim of our study was to assess the changing clinical spectrum of TAO in France during the past 40 years. All consecutive patients fulfilling TAO's criteria between January 1967 and January 2016 were retrospectively included in 3 departments of internal medicine. We compared TAO features in patients diagnosed before and after 2002; 141 (77.5%) men and 41 (22.5%) women were included. Patients diagnosed after 2002 were older (37 [31-39] vs 34 [29-35] years P = .03), had a more frequent isolated upper limb involvement (34.3% vs 7.8% P = .001), and less frequent isolated lower limb involvement (55.7% vs 74.5%, P < .001). The clinical spectrum of TAO has changed in France since the beginning of the 21st century.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arterias / Tromboangitis Obliterante / Fumar / Factores de Edad Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Angiology Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arterias / Tromboangitis Obliterante / Fumar / Factores de Edad Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Angiology Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos