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Dynamics of outcome after aneurysmal subarachnoid hemorrhage.
Hammer, Alexander; Ranaie, Gholamreza; Yakubov, Eduard; Erbguth, Frank; Holtmannspoetter, Markus; Steiner, Hans-Herbert; Janssen, Hendrik.
Afiliación
  • Hammer A; Department of Neurosurgery, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
  • Ranaie G; Department of Neurosurgery, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
  • Yakubov E; Department of Neurosurgery, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
  • Erbguth F; Department of Neurology, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
  • Holtmannspoetter M; Department of Neuroradiology, Nuremberg General Hospital, Nuremberg 90471, Bavaria, Germany.
  • Steiner HH; Department of Neurosurgery, Paracelsus Medical University, Nuremberg 90471, Bavaria, Germany.
  • Janssen H; Department of Neuroradiology, Ingolstadt General Hospital, Ingolstadt 85049, Bavaria, Germany.
Aging (Albany NY) ; 12(8): 7207-7217, 2020 04 20.
Article en En | MEDLINE | ID: mdl-32312942
In this observational study, we analyzed and described the dynamics of the outcome after aneurysmal subarachnoid hemorrhage (SAH) in a collective of 203 cases. We detected a significant improvement of the mean aggregate modified Rankin Score (mRS) in every time interval from discharge to 6 months and up to 1 year. Every forth to fifth patient with potential of recovery (mRS 1-5) at discharge improved by 1 mRS point in the time interval from 6 month to 1 year (22.6%). Patients with mRS 3 at discharge had a remarkable late recovery rate (73.3%, p = 0.000085). Multivariate analysis revealed age ≤ 65 years (odds ratio 4.93; p = 0.0045) and "World Federation of Neurological Surgeons" (WFNS) grades I and II (odds ratio 4.77; p = 0.0077) as significant predictors of early improvement (discharge to 6 months). Absence of a shunting procedure (odds ratio 8.32; p = 0.0049) was a significant predictor of late improvement (6 months to 1 year), but not age ≤ 65 years (p = 0.54) and WFNS grades I and II (p = 0.92). Thus, late recovery (6 month to 1 year) is significant and independent from age and WFNS grade.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemorragia Subaracnoidea / Aneurisma Intracraneal Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemorragia Subaracnoidea / Aneurisma Intracraneal Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos