Effect of Aldosterone on Senescence and Proliferation Inhibition of Endothelial Progenitor Cells Induced by Sirtuin 1 (SIRT1) in Pulmonary Arterial Hypertension.

Wang, Yue; Zhong, Bin; Wu, Qiyong; Tong, Jichun; Zhu, Tao; Zhang, Ming

Wang, Yue; Zhong, Bin; Wu, Qiyong; Tong, Jichun; Zhu, Tao; Zhang, Ming.

Afiliación

Wang Y; School of Pharmaceutical Engineering and Life Science and School of Nursing, Changzhou University, Changzhou, Jiangsu, China (mainland).
Zhong B; Department of Thoracic and Cardiovascular Surgery, Changzhou No. 2 People's Hospital, Affiliated to Nanjing Medical University, Changzhou, Jiangsu, China (mainland).
Wu Q; Department of Thoracic and Cardiovascular Surgery, Changzhou No. 2 People's Hospital, Affiliated to Nanjing Medical University, Changzhou, Jiangsu, China (mainland).
Tong J; Department of Thoracic and Cardiovascular Surgery, Changzhou No. 2 People's Hospital, Affiliated to Nanjing Medical University, Changzhou, Jiangsu, China (mainland).
Zhu T; Department of Thoracic and Cardiovascular Surgery, Changzhou No. 2 People's Hospital, Affiliated to Nanjing Medical University, Changzhou, Jiangsu, China (mainland).
Zhang M; Department of Thoracic and Cardiovascular Surgery, Changzhou No. 2 People's Hospital, Affiliated to Nanjing Medical University, Changzhou, Jiangsu, China (mainland).

Med Sci Monit ; 26: e920678, 2020 Apr 18.

Article en En | MEDLINE | ID: mdl-32303670

Asunto(s)

Aldosterona/farmacología; Hipertensión Arterial Pulmonar/metabolismo; Sirtuina 1/metabolismo; Animales; Proliferación Celular/efectos de los fármacos; Senescencia Celular/efectos de los fármacos; Inhibidor p21 de las Quinasas Dependientes de la Ciclina/metabolismo; Modelos Animales de Enfermedad; Células Progenitoras Endoteliales/efectos de los fármacos; Células Progenitoras Endoteliales/metabolismo; Células Progenitoras Endoteliales/patología; Masculino; Hipertensión Arterial Pulmonar/inducido químicamente; Hipertensión Arterial Pulmonar/patología; Ratas; Ratas Sprague-Dawley; Transducción de Señal/efectos de los fármacos; Sirtuina 1/antagonistas & inhibidores; Proteína p53 Supresora de Tumor/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aldosterona / Sirtuina 1 / Hipertensión Arterial Pulmonar Límite: Animals Idioma: En Revista: Med Sci Monit Asunto de la revista: MEDICINA Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

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