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Effect of health professional intervention on adherence to statin use according to the cause of patient non-adherence.
Oñatibia-Astibia, Ainhoa; Malet-Larrea, Amaia; Gastelurrutia, Miguel Ángel; Calvo, Begoña; Ramírez, Dulce; Cantero, Ignacio; Goyenechea, Estibaliz.
Afiliación
  • Oñatibia-Astibia A; Official Pharmacist Association of Gipuzkoa, Prim 2, 20006, Donostia/San Sebastian, Spain. ainhoaonatibia@redfarma.org.
  • Malet-Larrea A; Pharmaceutical Technology Department, Faculty of Pharmacy, Universidad del País Vasco UPV/EHU, P. Universidad 7, 01006, Vitoria, Spain. ainhoaonatibia@redfarma.org.
  • Gastelurrutia MÁ; Official Pharmacist Association of Gipuzkoa, Prim 2, 20006, Donostia/San Sebastian, Spain.
  • Calvo B; Pharmaceutical Care Research Group, Faculty of Pharmacy, University of Granada, Campus Universitario de Cartuja, 18071, Granada, Spain.
  • Ramírez D; Pharmaceutical Technology Department, Faculty of Pharmacy, Universidad del País Vasco UPV/EHU, P. Universidad 7, 01006, Vitoria, Spain.
  • Cantero I; Observatory of Adherence Treatment (OAT), Serrano 240-4, 28016, Madrid, Spain.
  • Goyenechea E; Observatory of Adherence Treatment (OAT), Serrano 240-4, 28016, Madrid, Spain.
Int J Clin Pharm ; 42(2): 331-335, 2020 Apr.
Article en En | MEDLINE | ID: mdl-32301066
Background Non-adherence is a problem that particularly affects those with chronic diseases. Studying causes for not following the treatment is necessary to choose the best intervention to improve non-adherence. Objective Analyze how the intentionality of non-adherence modulates the effects of professional intervention in patients with hypercholesterolemia. Setting: Community pharmacies and primary care centres in Spain. Methods A 6-month randomized controlled trial was conducted in 46 community pharmacies and 50 primary care centres in Spain. Adherence to statin therapy was measured with the Morisky-Green-Levine test. Non-adherence was classified based on the intentionality. Results 746 Patients were recruited for the study (465 non-adherent and 281 adherent). Of those, 237 were randomly assigned to the intervention group and 228 to the non-intervention group. The 56.5% of non-adherent patients were classified as unintentional non-adherents and 43.5% as intentional non-adherents. More patients in the intervention group finished being adherent compared with the non-intervention group (+ 17.2% for intentional non-adherents and + 27.4% for unintentional non-adherence). The percentage of patients in the intervention group who completed the study as adherent was higher among those who previously had unintentional non-adherence (66.4%) compared to those with intentional non- adherence (55.3%) (p < 0.001). Conclusion Intervention provided to patients with unintentional non-adherence was more effective than intervention provided to patients with intentional non- adherence.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Atención Primaria de Salud / Servicios Comunitarios de Farmacia / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Cumplimiento de la Medicación / Hipercolesterolemia Tipo de estudio: Clinical_trials Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Int J Clin Pharm Año: 2020 Tipo del documento: Article País de afiliación: España Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Atención Primaria de Salud / Servicios Comunitarios de Farmacia / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Cumplimiento de la Medicación / Hipercolesterolemia Tipo de estudio: Clinical_trials Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Int J Clin Pharm Año: 2020 Tipo del documento: Article País de afiliación: España Pais de publicación: Países Bajos