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Pain Relieving Effect of Intraoperative Chemical Splanchnicectomy of Celiac Ganglions in Patients with Resectable Pancreatic or Gastric Masses: A Randomized Clinical Trial.
Vahedian, Jalal; Saraee, Amir; Baghai Wadji, Massoud; Safari, Saeed; Chavoshi Khamneh, Abdolhamid.
Afiliación
  • Vahedian J; Iran University of Medical Sciences, Firoozgar Hospital, Tehran, Iran.
  • Saraee A; Iran University of Medical Sciences, Firoozgar Hospital, Tehran, Iran.
  • Baghai Wadji M; Iran University of Medical Sciences, Firoozgar Hospital, Tehran, Iran.
  • Safari S; Iran University of Medical Sciences, Firoozgar Hospital, Tehran, Iran.
  • Chavoshi Khamneh A; Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran.
Pain Res Manag ; 2020: 2675940, 2020.
Article en En | MEDLINE | ID: mdl-32300382
Background: Trials of intraoperative chemical splanchnicectomy during resection of pancreatic and gastric masses resulted in significant difference in a patient's postoperative pain. This study aims to determine if splanchnicectomy by alcohol neurolysis can relieve postoperative pain after gastrectomy and Whipple surgery. The study explores differences in outcomes at first four months after surgery. Methods: Fifty-eight patients with gastric and 60 patients with pancreatic resectable masses were included (28 were lost to follow-up). Each randomized in control and intervention subgroups. Intervention subgroups underwent chemical blockage of celiac ganglions by ethanol injection at both sides of suprapancreatic aorta. Participants were asked to report their pain intensity according to the Visual Analogue Scale (VAS) at specific times. Result: The overall postoperative pain of injected Whipple and gastrectomy subgroups was lower than the noninjected Whipple and gastrectomy subgroups (p < 0.001). The pain-modifying effect of the injection was not different between Whipple and gastrectomy groups (p=0.125). Conclusion: Splanchnicectomy is recommended for pain reduction after abdominal operations. Perspective. This article presents positive effect of intraoperative chemical splanchnicectomy during resection of pancreatic and gastric masses on postoperative pain. This is an easy, effective, safe, and inexpensive procedure recommended for all operable gastric or pancreatic masses to palliate the pain degree.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Postoperatorio / Procedimientos Quirúrgicos del Sistema Digestivo / Manejo del Dolor / Bloqueo Nervioso Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Pain Res Manag Asunto de la revista: NEUROLOGIA / PSICOFISIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Postoperatorio / Procedimientos Quirúrgicos del Sistema Digestivo / Manejo del Dolor / Bloqueo Nervioso Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Pain Res Manag Asunto de la revista: NEUROLOGIA / PSICOFISIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos