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Germline Elongator mutations in Sonic Hedgehog medulloblastoma.
Waszak, Sebastian M; Robinson, Giles W; Gudenas, Brian L; Smith, Kyle S; Forget, Antoine; Kojic, Marija; Garcia-Lopez, Jesus; Hadley, Jennifer; Hamilton, Kayla V; Indersie, Emilie; Buchhalter, Ivo; Kerssemakers, Jules; Jäger, Natalie; Sharma, Tanvi; Rausch, Tobias; Kool, Marcel; Sturm, Dominik; Jones, David T W; Vasilyeva, Aksana; Tatevossian, Ruth G; Neale, Geoffrey; Lombard, Bérangère; Loew, Damarys; Nakitandwe, Joy; Rusch, Michael; Bowers, Daniel C; Bendel, Anne; Partap, Sonia; Chintagumpala, Murali; Crawford, John; Gottardo, Nicholas G; Smith, Amy; Dufour, Christelle; Rutkowski, Stefan; Eggen, Tone; Wesenberg, Finn; Kjaerheim, Kristina; Feychting, Maria; Lannering, Birgitta; Schüz, Joachim; Johansen, Christoffer; Andersen, Tina V; Röösli, Martin; Kuehni, Claudia E; Grotzer, Michael; Remke, Marc; Puget, Stéphanie; Pajtler, Kristian W; Milde, Till; Witt, Olaf.
Afiliación
  • Waszak SM; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Robinson GW; Department of Oncology, Division of Neuro-Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Gudenas BL; Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Smith KS; Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Forget A; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France.
  • Kojic M; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
  • Garcia-Lopez J; Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Hadley J; Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Hamilton KV; Department of Oncology, Division of Cancer Predisposition, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Indersie E; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France.
  • Buchhalter I; Omics IT and Data Management Core Facility (W610), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Kerssemakers J; Omics IT and Data Management Core Facility (W610), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Jäger N; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Sharma T; Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Rausch T; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Kool M; Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Sturm D; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Jones DTW; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Vasilyeva A; Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Tatevossian RG; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
  • Neale G; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Lombard B; Pediatric Glioma Research Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Loew D; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Nakitandwe J; Pediatric Glioma Research Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Rusch M; Cancer Center Administration, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Bowers DC; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Bendel A; Hartwell Center, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Partap S; Institut Curie, PSL Research University, Centre de Recherche, Laboratoire de Spectrométrie de Masse Protéomique, Paris, France.
  • Chintagumpala M; Institut Curie, PSL Research University, Centre de Recherche, Laboratoire de Spectrométrie de Masse Protéomique, Paris, France.
  • Crawford J; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Gottardo NG; Department of Computational Biology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Smith A; Division of Pediatric Hematology-Oncology, University of Texas Southwestern Medical School, Dallas, TX, USA.
  • Dufour C; Department of Pediatric Hematology and Oncology, Children's Hospitals and Clinics of Minnesota, Minnesota, MN, USA.
  • Rutkowski S; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
  • Eggen T; Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA.
  • Wesenberg F; Department of Neurosciences, University of California San Diego and Rady Children's Hospital, San Diego, CA, USA.
  • Kjaerheim K; Department of Pediatrics, University of California San Diego and Rady Children's Hospital, San Diego, CA, USA.
  • Feychting M; Department of Paediatric and Adolescent Oncology/Haematology, Perth Children's Hospital and Brain Tumour Research Programme, Telethon Kids Institute, Perth, Western Australia, Australia.
  • Lannering B; Arnold Palmer Hospital Center for Children's Cancer, Orlando, FL, USA.
  • Schüz J; Gustave Roussy, Université Paris-Saclay, Department of Pediatric and Adolescent Oncology, Villejuif, France.
  • Johansen C; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Andersen TV; The Cancer Registry of Norway, Majorstuen, Oslo, Norway.
  • Röösli M; Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway.
  • Kuehni CE; Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway.
  • Grotzer M; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Remke M; Department of Pediatrics, University of Gothenburg, The Queen Silvia Children's Hospital, Gothenburg, Sweden.
  • Puget S; Section of Environment and Radiation, International Agency for Research on Cancer (IARC), Lyon, France.
  • Pajtler KW; Oncology Clinic, Finsen Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Milde T; Danish Cancer Society Research Center, Danish Cancer Society, Copenhagen, Denmark.
  • Witt O; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland.
Nature ; 580(7803): 396-401, 2020 04.
Article en En | MEDLINE | ID: mdl-32296180
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Mutación de Línea Germinal / Factores de Elongación Transcripcional / Meduloblastoma Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Child / Female / Humans / Male Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Mutación de Línea Germinal / Factores de Elongación Transcripcional / Meduloblastoma Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Child / Female / Humans / Male Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido