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Bite by a juvenile Bothrops venezuelensis (Venezuelan lancehead) resulting in severe envenomation: A case report.
Fuchs, Joan; Faber, Katrin; Tuchscherer, Daniel T; Tsakiris, Dimitrios A; Weiler, Stefan; Hofer, Katharina E.
Afiliación
  • Fuchs J; National Poisons Information Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich, Switzerland. Electronic address: joan.fuchs@toxinfo.ch.
  • Faber K; National Poisons Information Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich, Switzerland.
  • Tuchscherer DT; Department of Anesthesiology, Operative Intensive Care, Preclinical Emergency Medicine and Pain Management, University Hospital Basel, Basel, Switzerland.
  • Tsakiris DA; Department of Hematology, University Hospital Basel, Basel, Switzerland.
  • Weiler S; National Poisons Information Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich, Switzerland; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH, Zurich, Switzerland.
  • Hofer KE; National Poisons Information Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich, Switzerland.
Toxicon ; 180: 39-42, 2020 Jun.
Article en En | MEDLINE | ID: mdl-32289355
Bothrops venezuelensis is a venomous snake of the Viperidae family. It is associated with a high snakebite-related morbidity and mortality in Venezuela, although clinical case descriptions are scarce. Bites by other Bothrops sp. can result in coagulopathy and acute kidney injury. We describe a bite by a captive juvenile B. venezuelensis that caused local swelling, severe pain, endothelial damage, excessive fibrinolysis (INR >12, aPTT 136s, fibrinogen 0.3g/l) and incoagulable blood within 1.5 hours after the bite. The patient was treated with prothrombin complex factors concentrate, fibrinogen and antivenom (Antivipmyn®, Instituto Bioclon, Mexico) 4.5 h after the bite, which improved coagulation parameters progressively. Subsequently signs of compensated disseminated intravascular coagulation manifested and the patient received fresh frozen plasma and erythrocyte concentrate. The patient developed acute kidney injury with macroscopic hematuria. Fluid overload resulted in pulmonary edema requiring intermittent ventilation and diuretic treatment with furosemide. He was discharged with moderately elevated creatinine 16 days after hospitalization. Creatinine level normalized within another week. This case displays the life-threatening toxicity even after juvenile B. venezuelensis bites and the comparability to bites by other Bothrops sp.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mordeduras de Serpientes / Bothrops Límite: Adolescent / Animals / Humans / Male País/Región como asunto: America do sul / Venezuela Idioma: En Revista: Toxicon Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mordeduras de Serpientes / Bothrops Límite: Adolescent / Animals / Humans / Male País/Región como asunto: America do sul / Venezuela Idioma: En Revista: Toxicon Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido