Inhibition of Mitogen-Activated Protein Kinase Kinase Alone and in Combination with Anaplastic Lymphoma Kinase (ALK) Inhibition Suppresses Tumor Growth in a Mouse Model of ALK-Positive Lung Cancer.

Shrestha, N; Bland, A R; Bower, R L; Rosengren, R J; Ashton, J C

Shrestha, N; Bland, A R; Bower, R L; Rosengren, R J; Ashton, J C.

Afiliación

Shrestha N; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Bland AR; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Bower RL; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Rosengren RJ; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Ashton JC; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand john.ashton@otago.ac.nz.

J Pharmacol Exp Ther ; 374(1): 134-140, 2020 07.

Article en En | MEDLINE | ID: mdl-32284325

Asunto(s)

Quinasa de Linfoma Anaplásico/antagonistas & inhibidores; Neoplasias Pulmonares/patología; Quinasas de Proteína Quinasa Activadas por Mitógenos/antagonistas & inhibidores; Inhibidores de Proteínas Quinasas/farmacología; Animales; Bencimidazoles/farmacología; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Crizotinib/farmacología; Modelos Animales de Enfermedad; Interacciones Farmacológicas; Humanos; Ratones; Ensayos Antitumor por Modelo de Xenoinjerto

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinasas de Proteína Quinasa Activadas por Mitógenos / Inhibidores de Proteínas Quinasas / Quinasa de Linfoma Anaplásico / Neoplasias Pulmonares Límite: Animals / Humans Idioma: En Revista: J Pharmacol Exp Ther Año: 2020 Tipo del documento: Article País de afiliación: Nueva Zelanda Pais de publicación: Estados Unidos

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