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COVID-19 and Older Adults: What We Know.
Shahid, Zainab; Kalayanamitra, Ricci; McClafferty, Brendan; Kepko, Douglas; Ramgobin, Devyani; Patel, Ravi; Aggarwal, Chander Shekher; Vunnam, Ramarao; Sahu, Nitasa; Bhatt, Dhirisha; Jones, Kirk; Golamari, Reshma; Jain, Rohit.
Afiliación
  • Shahid Z; Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania.
  • Kalayanamitra R; Internal Medicine, Rowan University SOM, Stratford, New Jersey.
  • McClafferty B; Penn State College of Medicine, Hershey, Pennsylvania.
  • Kepko D; Emergency Medicine, Staten Island University Hospital, Zucker School of Medicine at Hofstra/Northwell, Staten Island, New York.
  • Ramgobin D; Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania.
  • Patel R; Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania.
  • Aggarwal CS; Touro College of Osteopathic Medicine, Middletown, New York.
  • Vunnam R; Department of Internal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Sahu N; University College of Medical Sciences Delhi, Delhi, India.
  • Bhatt D; Department of Internal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Jones K; Department of Internal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Golamari R; Department of Internal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Jain R; Department of Pharmacy, Western Maryland Health System, Cumberland, Maryland.
J Am Geriatr Soc ; 68(5): 926-929, 2020 05.
Article en En | MEDLINE | ID: mdl-32255507
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel virus that causes COVID-19 infection, has recently emerged and caused a deadly pandemic. Studies have shown that this virus causes worse outcomes and a higher mortality rate in older adults and those with comorbidities such as hypertension, cardiovascular disease, diabetes, chronic respiratory disease, and chronic kidney disease (CKD). A significant percentage of older American adults have these diseases, putting them at a higher risk of infection. Additionally, many adults with hypertension, diabetes, and CKD are placed on angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers. Studies have shown that these medications upregulate the ACE-2 receptor, the very receptor that the SARS-CoV-2 virus uses to enter host cells. Although it has been hypothesized that this may cause a further increased risk of infection, more studies on the role of these medications in COVID-19 infections are necessary. In this review, we discuss the transmission, symptomatology, and mortality of COVID-19 as they relate to older adults, and possible treatments that are currently under investigation. J Am Geriatr Soc 68:926-929, 2020.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones por Coronavirus / Pandemias Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Aged / Humans Idioma: En Revista: J Am Geriatr Soc Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones por Coronavirus / Pandemias Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Aged / Humans Idioma: En Revista: J Am Geriatr Soc Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos