[Mutagenic properties of phosphotriester analogs of oligodeoxyribonucleotides]. / Mutagennye svoistva fosfotriéfirnykh analogov oligodezoksiribonukleidov.
Mol Biol (Mosk)
; 22(5): 1226-37, 1988.
Article
en Ru
| MEDLINE
| ID: mdl-3221851
The high effectivity of using phosphotriester analogs of oligonucleotides for aimed mutagenesis in vitro and in vivo was shown. A general scheme, describing the mutagenic effects of phosphotriester analogs of oligonucleotides and their natural homologs, was derived by analysis of data on the structures of the obtained mutants. This scheme can serve as a foundation for selecting the structure of effective agents for aimed mutagenesis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Oligodesoxirribonucleótidos
/
Compuestos Organofosforados
/
Organofosfatos
/
Mutágenos
Idioma:
Ru
Revista:
Mol Biol (Mosk)
Año:
1988
Tipo del documento:
Article
Pais de publicación:
Rusia