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Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations.
Ogino, Atsuko; Choi, Jihyun; Lin, Mika; Wilkens, Margaret K; Calles, Antonio; Xu, Man; Adeni, Anika E; Chambers, Emily S; Capelletti, Marzia; Butaney, Mohit; Gray, Nathanael S; Gokhale, Prafulla C; Palakurthi, Sangeetha; Kirschmeier, Paul; Oxnard, Geoffrey R; Sholl, Lynette M; Jänne, Pasi A.
Afiliación
  • Ogino A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Choi J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Lin M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wilkens MK; Experimental Therapeutics Core, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Calles A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Xu M; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Adeni AE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Chambers ES; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Capelletti M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Butaney M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Gray NS; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Gokhale PC; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Palakurthi S; Experimental Therapeutics Core, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Kirschmeier P; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Oxnard GR; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Sholl LM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Jänne PA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Mol Oncol ; 15(1): 27-42, 2021 01.
Article en En | MEDLINE | ID: mdl-32191822
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Heterogeneidad Genética / Carcinoma Pulmonar de Células Pequeñas / Terapia Molecular Dirigida / Fumadores / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Oncol Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Heterogeneidad Genética / Carcinoma Pulmonar de Células Pequeñas / Terapia Molecular Dirigida / Fumadores / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Oncol Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos